Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• MAZIE: a mass and charge inference engine to enhance database searching of tandem mass spectra.

  PMID 19850495 · PMC2818324 · Journal of the American Society for Mass Spectrometry · 2010 · 7 claims · 4 setups

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  MAZIE is a post-acquisition Perl algorithm that determines precursor ion monoisotopic mass and charge (+1 to +4) from MS1 zoom scan isotopic distributions on a Thermo LTQ-XL

  urine same lc-ms2 ms1 comparative

• Analysis of a photosynthetic cyanobacterium rich in internal membrane systems via gradient profiling by sequencing (Grad-seq).

  PMID 33793824 · PMC8136920 · The Plant cell · 2021 · 8 claims · 6 setups

  Has reproduction · 100

  Grad-seq resolves complexes with overlapping subunits, such as CpcG1-type versus CpcL-type phycobilisomes or PsaK1 versus PsaK2 photosystem I (pre)complexes, validating the approach.

  synechocystis gradient proteins grad-seq grad-seq denaturing sds-polyacrylamide

• One-pot shotgun quantitative mass spectrometry characterization of histones.

  PMID 19764812 · PMC2798817 · Journal of proteome research · 2009 · 8 claims · 8 setups

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  One-pot propionylation and trypsin digestion of unfractionated bulk histones enables quantitative Bottom Up MS characterization of histone PTMs without prior off-line HPLC or SDS-PAGE purification

  hela wild-type set2δ yeast bottom rp-hplc one-pot