Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Full-text index only
Genomics: applications in mechanism elucidation.
PMID 19166886 · PMC2698023 · Advanced drug delivery reviews · 2009 · 8 claims · 8 setups
Genomic tools require no a priori knowledge of a compound's mode of action and can reveal biological pathways (metabolism, distribution, off-target effects) in addition to the precise mechanism of action.
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Has reproduction · 83
Transcription-coupled and epigenome-encoded mechanisms direct H3K4 methylation.
PMID 35953471 · PMC9372134 · Nature communications · 2022 · 8 claims · 8 setups
ATX1, ATX2, and ATXR7 redundantly mediate H3K4 monomethylation genome-wide