Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Ensemble of Time-Evolving SASP Gene Sets Identifies IGFBP7 and CDKN1A as a Potential Marker Pair for Senescent Fibroblast Subpopulations Across Tissues.

  PMID 41977201 · PMC13073673 · International journal of molecular sciences · 2026 · 8 claims · 5 setups

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  SASP genes are not uniformly expressed in all senescent fibroblasts but only in specific subpopulations, indicating combinatorial and heterogeneous SASP expression.

  wi-38 lung skin eye scrna-seq computational

• Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.

  PMID 41746734 · PMC13043084 · JCI insight · 2026 · 8 claims · 8 setups

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  The dG-MYRF C-terminal frameshift variant undergoes normal homotrimerization, cleavage, and nuclear localization but shows reduced steady-state levels of the C-terminal cleavage product and decreased transcriptional activation of target genes.

  arpe-19 myrf rpe e17.5 immunofluorescence computational cycloheximide

• Looping specificity of Polycomb response elements requires GAF and a combination of looping factors that could form a code.

  PMID 42206359 · PMC13216745 · Nucleic acids research · 2026 · 8 claims · 8 setups

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  High GAF occupancy is required for chromatin looping and gene regulation at PREs

  drosophila third gaf dac_tss cut&run micro-c hi-c