Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Magnetically assisted DNA assays: high selectivity using conjugated polymers for amplified fluorescent transduction.
PMID 15905472 · PMC1131937 · Nucleic acids research · 2005 · 8 claims · 8 setups
Introducing streptavidin-coated magnetic microparticles (MMPs) into a sandwich-type CP-based DNA sensor significantly improves selectivity against non-cognate DNA compared with previously reported CP-amplified sensors.
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Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide arrays.
PMID 15099405 · PMC411067 · BMC bioinformatics · 2004 · 7 claims · 2 setups
Two-way ANOVA and Mack-Skillings tests on probe-level data with FDR control are substantially more powerful than t-test/Wilcoxon on probe-set level data for detecting differential expression
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Has reproduction · 71
Chemical genomics informs antibiotic and essential gene function in Acinetobacter baumannii.
PMID 40153700 · PMC11975115 · PLoS genetics · 2025 · 8 claims · 6 setups
The vast majority of A. baumannii essential genes show significant chemical-gene interactions upon knockdown
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Proposed methods for testing and selecting the ERCC external RNA controls.
PMID 16266432 · PMC1325234 · BMC genomics · 2005 · 8 claims · 5 setups
A consortium-developed, standardized set of external RNA control transcripts can be used to assess technical performance in gene expression assays (microarray and QRT-PCR)
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Has reproduction · 74
Disome-seq reveals widespread ribosome collisions that promote cotranslational protein folding.
PMID 33402206 · PMC7784341 · Genome biology · 2021 · 8 claims · 8 setups
Disome-seq sequences mRNA fragments protected by two stacked (collided) ribosomes, detecting ribosome collisions at codon resolution.
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One-pot shotgun quantitative mass spectrometry characterization of histones.
PMID 19764812 · PMC2798817 · Journal of proteome research · 2009 · 8 claims · 8 setups
One-pot propionylation and trypsin digestion of unfractionated bulk histones enables quantitative Bottom Up MS characterization of histone PTMs without prior off-line HPLC or SDS-PAGE purification