Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Comprehensive cellular analysis with single-nucleus RNA-seq of archived PAXgene whole blood samples.

  PMID 41844163 · PMC13030975 · Cell reports methods · 2026 · 8 claims · 7 setups

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  Cell lysis (CL) nuclei isolation yields substantially more nuclei and less biased immune cell proportions than mechanical separation (MS)

  frozen paxgene cl-derived thawed single-nucleus confocal brightfield

• Disruption of metabolic licensing by JAK inhibitors constrains CD8 T cell activation and effector function.

  PMID 41876467 · PMC13039990 · Cell death & disease · 2026 · 8 claims · 8 setups

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  JAKis targeting JAK1, JAK1/2, or JAK1/3 markedly reduce CD8 T cell activation markers, proliferation, and effector molecule (TNF, granzyme B) production

  naive memory activated sorted flow scenith cd8

• CD69 regulates the tissue dynamics of epigenetically imprinted memory CD4(+) T cells.

  PMID 41950321 · PMC13060599 · Science advances · 2026 · 8 claims · 8 setups

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  CD69 is essential for tissue retention of CD4+ TRM cells in inflamed lungs, in both allergic (HDM/OVA) and infectious (BCG) models

  ova-specific lung thy1.1+ peripheral adoptive flow parabiosis