Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 5

System / cell line: sirna ✕ Assay: confocal ✕ Clear

Point mutations in GLI3 lead to misregulation of its subcellular localization.

PMID 19829694 · PMC2758996 · PloS one · 2009 · 6 claims · 8 setups

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The MID1-α4-PP2A complex regulates the subcellular localization and transcriptional activity of GLI3.

hela immunofluorescence real-time luciferase
PAF15-PCNA exhaustion governs the strand-specific control of DNA replication.

PMID 41606318 · PMC12979207 · Nature · 2026 · 8 claims · 8 setups

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Excessive origin firing saturates chromatin-bound PCNA, restricting further PCNA loading and lagging-strand synthesis when checkpoint control is lost.

u2os embryonic qibc confocal western
CD155/PVR plays a key role in cell motility during tumor cell invasion and migration.

PMID 15471548 · PMC524493 · BMC cancer · 2004 · 8 claims · 8 setups

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A FALI-coupled scFv antibody library screen identifies CD155 (poliovirus receptor) as a mediator of tumor cell invasion

ht1080 u87mg normal 96-well transwell immunoblot
Proteomic screen defines the hepatocyte nuclear factor 1alpha-binding partners and identifies HMGB1 as a new cofactor of HNF1alpha.

PMID 18160415 · PMC2275099 · Nucleic acids research · 2008 · 8 claims · 8 setups

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HMGB1 is a novel HNF1α-interacting protein identified via a co-IP-MS screening strategy

hepg2 recombinant co-immunoprecipitation immunofluorescence gst
The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90.

PMID 18726985 · PMC2826114 · The Prostate · 2008 · 7 claims · 8 setups

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Quercetin treatment of prostate cancer cells decreases cell proliferation and viability in a dose-dependent manner

pc-3 excised prostate viability difference nano

Experiments

Point mutations in GLI3 lead to misregulation of its subcellular localization.

PAF15-PCNA exhaustion governs the strand-specific control of DNA replication.

CD155/PVR plays a key role in cell motility during tumor cell invasion and migration.

Proteomic screen defines the hepatocyte nuclear factor 1alpha-binding partners and identifies HMGB1 as a new cofactor of HNF1alpha.

The dietary bioflavonoid, quercetin, selectively induces apoptosis of prostate cancer cells by down-regulating the expression of heat shock protein 90.