Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Phosphoproteomics: new insights into cellular signaling.
PMID 16168091 · PMC1242200 · Genome biology · 2005 · 8 claims · 8 setups
Protein kinases are one of the largest gene families in humans and mice, accounting for 1.7% of the human genome
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Protein interaction networks by proteome peptide scanning.
PMID 14737190 · PMC314469 · PLoS biology · 2004 · 8 claims · 7 setups
WISE (combining phage display-derived relaxed consensus patterns with SPOT peptide synthesis arrays) can identify proteome-wide binding partners of a peptide-recognition domain
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Fast and systematic genome-wide discovery of conserved regulatory elements using a non-alignment based approach.
PMID 15693947 · PMC551538 · Genome biology · 2005 · 7 claims · 8 setups
FastCompare, a non-alignment-based, linear-time algorithm, computes a genome-wide conservation score for all k-mers (7-9 nt) between two genomes to identify conserved regulatory elements
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Has reproduction · 68
LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq.
PMID 24709818 · PMC4079972 · Genome research · 2014 · 8 claims · 8 setups
LaSSO (Lariat Sequence Site Origin) identifies intronic lariat reads and pinpoints branch points genome-wide from RNA-seq data by considering every intronic base as a potential branch point and including all possible exon-skipping lariats.
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Ensembl 2006.
PMID 16381931 · PMC1347495 · Nucleic acids research · 2006 · 8 claims · 5 setups
Ensembl now provides annotation for 19 genomes, up from 4 the previous year, including new mammalian (Rhesus macaque, Opossum), chordate (Ciona intestinalis), and yeast genomes.
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Identification of RNA-Binding Protein Targets with HyperTRIBE in Saccharomyces cerevisiae.
PMID 37240377 · PMC10218906 · International journal of molecular sciences · 2023 · 7 claims · 8 setups
HyperTRIBE was successfully established in S. cerevisiae by fusing an RBP to the hyper-active catalytic domain of human ADAR2 (E488Q), marking target transcripts with A-to-G editing events detectable by high-throughput sequencing
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PeroxisomeDB: a database for the peroxisomal proteome, functional genomics and disease.
PMID 17135190 · PMC1747181 · Nucleic acids research · 2007 · 8 claims · 6 setups
PeroxisomeDB integrates the complete peroxisomal proteome of Homo sapiens and Saccharomyces cerevisiae into interrelated 'Genes', 'Functions', 'Metabolic pathways' and 'Diseases' sections with links to NCBI, ENSEMBL and UCSC
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The TIGR Gene Indices: clustering and assembling EST and known genes and integration with eukaryotic genomes.
PMID 15608288 · PMC540018 · Nucleic acids research · 2005 · 8 claims · 8 setups
The TIGR Gene Indices (TGI) are a collection of 77 species-specific databases that cluster and assemble EST and known gene sequences into tentative consensus (TC) sequences to identify and characterize expressed transcripts.
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Cryptosporidium: genomic and biochemical features.
PMID 19187778 · PMC2819285 · Experimental parasitology · 2010 · 8 claims · 8 setups
C. parvum lacks a plastid and mitochondrial genome, unlike other apicomplexans, limiting plastid-targeted drug strategies