Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Neuroacanthocytosis associated with a defect of the 4.1R membrane protein.
PMID 17298666 · PMC1805452 · BMC neurology · 2007 · 8 claims · 8 setups
Four unrelated NA patients show a novel erythrocyte membrane defect: 4.1R protein deficiency
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Predicting failure rate of PCR in large genomes.
PMID 18492719 · PMC2441781 · Nucleic acids research · 2008 · 7 claims · 8 setups
The number of predicted primer-binding sites in genomic DNA is the most important factor determining PCR failure.
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CorGen--measuring and generating long-range correlations for DNA sequence analysis.
PMID 16845099 · PMC1538783 · Nucleic acids research · 2006 · 8 claims · 3 setups
CorGen is a web server that measures long-range correlations in DNA sequences and generates random sequences with the same (or user-specified) correlation and composition parameters
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Has reproduction · 92
Draft Genome Sequences of Antimicrobial-Resistant Shigella Clinical Isolates from Pakistan.
PMID 31346012 · PMC6658682 · Microbiology resource announcements · 2019 · 6 claims · 6 setups
Draft genome sequences are reported for three multidrug-resistant Shigella clinical isolates from Pakistan (two S. flexneri and one S. sonnei).
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Reverse polarization in amino acid and nucleotide substitution patterns between human-mouse orthologs of two compositional extrema.
PMID 17895298 · PMC2533592 · DNA research : an international journal for rapid publication of reports on genes and genomes · 2007 · 8 claims · 7 setups
Nucleotide and amino acid substitution trends between human-mouse orthologs are highly asymmetric and polarized in opposite directions for high-GC versus low-GC gene groups.
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Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii.
PMID 18282098 · PMC2242837 · PLoS pathogens · 2008 · 8 claims · 6 setups
A high-throughput ENU mutagenesis screen isolated 165 temperature-sensitive (ts) Toxoplasma growth mutants from ~60,000 clones.
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Exploring the immunome: A brave new world for human vaccine development.
PMID 20009527 · PMC2919815 · Human vaccines · 2009 · 7 claims · 7 setups
Screening the Mtb proteome in silico for epitopes ('fishing for antigens using epitopes as bait') revealed a remarkable diversity of human immune responses to Mtb proteins without an ascribed function, suggesting human immune response to Mtb is omnivorous rather than focused on single immunodominant proteins.
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Has reproduction · 89
Comparative genomics of dairy-associated Staphylococcus aureus from selected sub-Saharan African regions reveals milk as reservoir for human-and animal-derived strains and identifies a putative animal-related clade with presumptive novel siderophore.
PMID 36046020 · PMC9421002 · Frontiers in microbiology · 2022 · 7 claims · 8 setups
Milk serves as a reservoir for both human- and animal-derived S. aureus strains in sub-Saharan Africa
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Comparative genomics of multidrug resistance in Acinetobacter baumannii.
PMID 16415984 · PMC1326220 · PLoS genetics · 2006 · 7 claims · 5 setups
A. baumannii strain AYE contains an 86-kb genomic resistance island (AbaR1) clustering 45 of its 52 resistance genes, the largest resistance island described to date
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Molecular correlates of host specialization in Staphylococcus aureus.
PMID 17971880 · PMC2040198 · PloS one · 2007 · 8 claims · 6 setups
Genome sequencing of ET3-1 revealed genomic elements not previously identified in S. aureus, including homologs of virulence factors from other Gram-positive pathogens
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Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium.
PMID 19781061 · PMC2768977 · Genome biology · 2009 · 8 claims · 7 setups
The 027 genomes (CD196 and R20291) contain 234 additional genes compared to strain 630, spread across at least 50 regions of genetic difference, including a phage island, transposon genes, two-component response regulators, drug resistance genes and transporters
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Has reproduction · 63
Comparative Genomics of Borderline Oxacillin-Resistant Staphylococcus aureus Detected during a Pseudo-outbreak of Methicillin-Resistant S. aureus in a Neonatal Intensive Care Unit.
PMID 35038924 · PMC8764539 · mBio · 2022 · 7 claims · 8 setups
Of 42 isolates flagged as MRSA by screening agar, only 9 were PBP2a- and mecA-positive true MRSA, while the remaining 33 were mecA-negative and largely met criteria for BORSA
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Characterisation of the genomic architecture of human chromosome 17q and evaluation of different methods for haplotype block definition.
PMID 15850495 · PMC1090572 · BMC genetics · 2005 · 8 claims · 6 setups
Haplotype block definitions based on LD measures (Definitions 1, 2, 3, 5) produce fewer, shorter blocks with limited sequence coverage compared to the haplotype diversity-based method (Definition 4)
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Does distance matter? Variations in alternative 3' splicing regulation.
PMID 17704130 · PMC2018619 · Nucleic acids research · 2007 · 8 claims · 7 setups
Alternative 3' splice sites can be distinguished from constitutive splice sites by a combination of sequence/conservation properties that vary depending on the distance between the splice sites.
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The meso-genomic era.
PMID 11516332 · PMC139414 · Genome biology · 2001 · 8 claims · 8 setups
Linkage disequilibrium (LD) between SNPs extends much further in Northern European populations (~120 kb) than in a Nigerian population (<10 kb), reflecting differing population histories (bottlenecks vs. constant expansion).