Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 53
spliceJAC: transition genes and state-specific gene regulation from single-cell transcriptome data.
PMID 36321549 · PMC9627675 · Molecular systems biology · 2022 · 8 claims · 8 setups
spliceJAC uses unspliced and spliced mRNA count matrices to construct cell state-specific gene-gene regulatory interaction (Jacobian) matrices from scRNA-seq data
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Metagenomic Comparison of Bat Colony Resistomes Across Anthropogenic and Pristine Habitats.
PMID 41594088 · PMC12838372 · Antibiotics (Basel, Switzerland) · 2026 · 8 claims · 7 setups
Anthropogenic exposure enhances the diversity and evenness of resistance mechanisms within bat-associated microbiomes, increasing their potential as AMR reservoirs.
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Bayesian model accounting for within-class biological variability in Serial Analysis of Gene Expression (SAGE).
PMID 15339345 · PMC517707 · BMC bioinformatics · 2004 · 7 claims · 5 setups
A Bayesian mixture model is proposed to account for within-class biological variability in SAGE/Digital-Northern/MPSS tag counting data.
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Has reproduction · 75
geneshot: gene-level metagenomics identifies genome islands associated with immunotherapy response.
PMID 33952321 · PMC8097837 · Genome biology · 2021 · 8 claims · 6 setups
geneshot identifies microbial genomic islands consistently associated with ICI response across independent cohorts
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Protocol to perform cell-type-specific transcriptome-wide association study using scPrediXcan framework.
PMID 41689808 · PMC12925207 · STAR protocols · 2026 · 6 claims · 6 setups
scPrediXcan enables cell-type-specific transcriptome-wide association studies (TWAS) by integrating deep learning-based prediction of gene expression from DNA sequence and epigenetic features.
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Recent additions and improvements to the Onto-Tools.
PMID 15980579 · PMC1160233 · Nucleic acids research · 2005 · 7 claims · 3 setups
The Onto-Tools back-end database was redesigned around the Entrez Gene data model after NCBI phased out LocusLink in February 2005.
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Has reproduction · 68
Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing.
PMID 31443728 · PMC6708158 · Genome medicine · 2019 · 6 claims · 8 setups
A near-perfect chronological age predictor can in principle be developed from DNA methylation when training sample size is sufficiently large.
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Comparative genomics of multidrug resistance in Acinetobacter baumannii.
PMID 16415984 · PMC1326220 · PLoS genetics · 2006 · 7 claims · 5 setups
A. baumannii strain AYE contains an 86-kb genomic resistance island (AbaR1) clustering 45 of its 52 resistance genes, the largest resistance island described to date
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Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1.
PMID 17967058 · PMC2042017 · PLoS pathogens · 2007 · 8 claims · 8 setups
APOBEC3C is necessary and sufficient to induce G-to-A mutation in some HIV-1 strains despite Vif expression