Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Integrative miRNA-mRNA Network and Molecular Dynamics-Based Identification of Therapeutic Candidates for Paroxysmal Nocturnal Hemoglobinuria.

  PMID 41599741 · PMC12845513 · Pharmaceuticals (Basel, Switzerland) · 2026 · 8 claims · 8 setups

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  A PIGA-knockout (PIGA-KO) THP-1 cell model was successfully established using CRISPR/Cas9 RNP technology as a PNH model

  thp-1 literature-validated pnh cxcl8 crispr rt-qpcr bulk

• scMILD: Single-cell multiple instance learning for sample classification and associated subpopulation discovery.

  PMID 41907409 · PMC13019583 · iScience · 2026 · 8 claims · 8 setups

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  scMILD identifies condition-associated cells using only sample-level labels via a dual-branch MIL architecture with a shared encoder

  simulated lupus covid-19 ulcerative simulated mixture scrna-seq

• Genome-scale modeling identifies dynamic metabolic vulnerabilities during the epithelial to mesenchymal transition.

  PMID 39730911 · PMC11681178 · Communications biology · 2024 · 8 claims · 8 setups

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  EMT involves temporal, stage-specific metabolic reprogramming with distinct dependencies in glycolysis and glutamine metabolism.

  a549 recon1 cancer lung bulk single-cell genome-scale

• Discovery and characterization of gene-by-environment and epistatic genetic effects in a vertebrate model.

  PMID 41672067 · PMC13174225 · Cell genomics · 2026 · 7 claims · 7 setups

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  A segregation analysis in an F2 medaka cross identified 16 QTLs linked to embryonic heart rate variation across temperatures

  mikk medaka discovered informed high-throughput heart shallow

• Chromatin architecture reprogramming reveals novel epigenetic dependencies in breast cancer.

  PMID 41412800 · PMC12849445 · Genes & development · 2026 · 7 claims · 7 setups

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  H3K9 methylation and the demethylase KDM4C, through association with SWI/SNF, drive proliferation of cells fated to become endocrine-resistant via a nongenomic estrogen-mediated mechanism

  parental t47d esr1 scrna-seq hi-c atac-seq