Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.
PMID 41564866 · PMC12866162 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
CHD1 and MAP3K7 loss additively sensitizes cancer cells to IFN-γ-induced death
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Has reproduction · 68
Complete Genome Sequencing of Lactobacillus plantarum ZLP001, a Potential Probiotic That Enhances Intestinal Epithelial Barrier Function and Defense Against Pathogens in Pigs.
PMID 30542296 · PMC6277807 · Frontiers in physiology · 2018 · 8 claims · 8 setups
The complete genome of L. plantarum ZLP001 was sequenced and compared with 18 other L. plantarum genomes to identify genomic features underlying its gut-health-promoting probiotic properties.
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Has reproduction · 68
Genome-wide DNA hypermethylation opposes healing in patients with chronic wounds by impairing epithelial-mesenchymal transition.
PMID 35819852 · PMC9433101 · The Journal of clinical investigation · 2022 · 8 claims · 8 setups
Chronic wound-edge tissue shows genome-wide DNA hypermethylation compared with unwounded skin
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Has reproduction · 54
A 14-bp motif in the KIT active promoter region is critical for melanin accumulation in yaks, mice, and humans.
PMID 40629379 · PMC12239316 · BMC biology · 2025 · 8 claims · 7 setups
A 14-bp deletion in the KIT gene promoter region is associated with the all-white phenotype in yaks, identified via GWAS
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Cis-regulatory evolution reveals sensory trade-offs as a genetic basis for temporal niche evolution in tapirs.
PMID 41779860 · PMC12959415 · Science advances · 2026 · 8 claims · 8 setups
Tapirs reverted from a cathemeral ancestor to a nocturnal/crepuscular niche, accompanied by coordinated sensory reallocation: regressive vision (corneal opacity, reduced acuity) with enhanced auditory and chemosensory systems.
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Developmental convergence and divergence in human stem cell models of autism.
PMID 41611887 · PMC12999519 · Nature · 2026 · 8 claims · 8 setups
Different ASD-associated mutations show the largest mutation-specific transcriptional changes early in hCO differentiation but converge on shared transcriptional changes as development progresses
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Homeodomain protein Sxi1α independently controls cell-cell fusion and gene expression during sexual reproduction in Cryptococcus deneoformans.
PMID 41818280 · PMC13001979 · PLoS genetics · 2026 · 8 claims · 8 setups
Sxi1α has a previously unrecognized inhibitory role in same-sex (α-α) cell-cell fusion during unisexual reproduction
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Has reproduction · 68
Targeting the epigenome and the integrated stress response to normalize colorectal cancer subclonal plasticity and progression.
PMID 41963303 · PMC13181133 · Cell death & disease · 2026 · 8 claims · 8 setups
The integrated stress response (ISR) induces CRC cell plasticity, subclonal diversity, and tumor progression in stress-surviving cells
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Discovery and characterization of gene-by-environment and epistatic genetic effects in a vertebrate model.
PMID 41672067 · PMC13174225 · Cell genomics · 2026 · 7 claims · 7 setups
A segregation analysis in an F2 medaka cross identified 16 QTLs linked to embryonic heart rate variation across temperatures
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Remodeling of XIST regulatory landscape during primate evolution.
PMID 41544163 · PMC12810636 · Science advances · 2026 · 8 claims · 8 setups
XIST regulation has diverged uniquely and rapidly between closely related primates: JPX is a major XIST regulator in human and marmoset ESCs but only a minor regulator in macaque ESCs