Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Atlas - a data warehouse for integrative bioinformatics.
PMID 15723693 · PMC554782 · BMC bioinformatics · 2005 · 8 claims · 3 setups
Atlas is a biological data warehouse that locally stores and integrates sequences, molecular interactions, homology information, functional annotations, and ontologies
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Identification and evolutionary analysis of novel exons and alternative splicing events using cross-species EST-to-genome comparisons in human, mouse and rat.
PMID 16536879 · PMC1479377 · BMC bioinformatics · 2006 · 8 claims · 6 setups
ENACE, a cross-species EST-to-genome comparison algorithm, can identify novel cassette-on exons and retained introns for EST-scanty species and distinguish conserved vs lineage-specific exons
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Organization of physical interactomes as uncovered by network schemas.
PMID 18949022 · PMC2561054 · PLoS computational biology · 2008 · 7 claims · 5 setups
A computational procedure can systematically identify 'emergent' network schemas that are both recurrent and over-represented relative to randomized networks preserving lower-order subschema distributions
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Protein function assignment through mining cross-species protein-protein interactions.
PMID 18253506 · PMC2216687 · PloS one · 2008 · 8 claims · 6 setups
CSIDOP predicts protein molecular function with 95.42% accuracy using 2,972 GO functional categories in H. sapiens
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WebScipio: an online tool for the determination of gene structures using protein sequences.
PMID 18801164 · PMC2644328 · BMC genomics · 2008 · 7 claims · 4 setups
WebScipio, a web interface to Scipio, determines gene structure from a query protein sequence against an assembled eukaryotic genome with quality approaching manual annotation.
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miRGen: a database for the study of animal microRNA genomic organization and function.
PMID 17108354 · PMC1669779 · Nucleic acids research · 2007 · 8 claims · 6 setups
miRGen is an integrated database combining Genomics, Targets, and Clusters interfaces to study miRNA genomic organization and function across 11 animal genomes
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An optimized procedure for the design and evaluation of Ecotilling assays.
PMID 18973671 · PMC2586031 · BMC genomics · 2008 · 8 claims · 7 setups
An optimized procedure integrating Vector NTI, Ensembl, Genomatix Suite, GelBuddy, and sequencing/functional-prediction tools streamlines the design, evaluation and interpretation of human Ecotilling assays
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Steps toward broad-spectrum therapeutics: discovering virulence-associated genes present in diverse human pathogens.
PMID 19874620 · PMC2774872 · BMC genomics · 2009 · 8 claims · 8 setups
Phylogenetic profiling of protein clusters across pathogen and non-pathogen genomes can identify candidate generic virulence factors