Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Resolving clonal evolution and selection of extrachromosomal DNA at single-cell resolution.

  PMID 41606654 · PMC12853921 · Genome biology · 2026 · 7 claims · 8 setups

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  ecSingle, a computational method integrating allelic imbalance (BAF deviation) and outlier expression from scRNA-seq, can identify oncogene-carrying ecDNA at single-cell resolution.

  colo320dm glioblastoma medulloblastoma ce26 scrna-seq whole-genome long-read

• Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations.

  PMID 19654296 · PMC2763410 · Cancer research · 2009 · 7 claims · 7 setups

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  CHASM, a Random Forest-based computational method, was developed to identify and prioritize missense mutations likely to be functional drivers of tumor cell proliferation.

  missense same synthetic tp53 random support principal