Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 4

System / cell line: qpcr ✕ Assay: crystal ✕ Clear

Activating GCN2 and subsequently the Unfolded Protein Response with the small oral molecule NXP800 delays tumor growth in osteosarcoma.

PMID 41644942 · PMC12895007 · Cell death discovery · 2026 · 7 claims · 13 setups

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NXP800 decreases viability of osteosarcoma cell lines by blocking proliferation and inducing apoptosis

mnng gcn2-gst nmri crystal clonogenic cycle
Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes.

PMID 18003658 · PMC2248751 · Nucleic acids research · 2008 · 8 claims · 8 setups

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p110 CUX1 is recruited to promoters of cell cycle-related target genes preferentially during S phase

hela hs578t nih3t3 genomic chap-chip conventional scanning
Leveraging the germ layer development patterns to predict prognosis and identify MEST as a novel therapeutic target in glioma.

PMID 41501725 · PMC12870398 · Cancer cell international · 2026 · 7 claims · 8 setups

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MEST is a key oncogenic GLD-related gene and a novel therapeutic target in glioma, identified via a machine learning feature selection framework

bulk single-cell tcga glioma gsva aucell machine
A P4HA2 hypoxia signature derived from single cell atlas stratifies conserved subtypes with prognostic significance in cervical squamous cell carcinoma.

PMID 41559646 · PMC12910786 · BMC cancer · 2026 · 6 claims · 8 setups

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A tumor cell metaprogram (MP7) identified from scRNA-seq of CSCC shows elevated hypoxia, invasion, metastasis, proliferation, and angiogenesis scores compared to other metaprograms.

cscc tcga-cscc mp7 siha single-cell bulk gene

Experiments

Activating GCN2 and subsequently the Unfolded Protein Response with the small oral molecule NXP800 delays tumor growth in osteosarcoma.

Genome-wide location analysis and expression studies reveal a role for p110 CUX1 in the activation of DNA replication genes.

Leveraging the germ layer development patterns to predict prognosis and identify MEST as a novel therapeutic target in glioma.

A P4HA2 hypoxia signature derived from single cell atlas stratifies conserved subtypes with prognostic significance in cervical squamous cell carcinoma.