Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 65
β-Catenin activity induces an RNA biosynthesis program promoting therapy resistance in T-cell acute lymphoblastic leukemia.
PMID 36597789 · PMC9906382 · EMBO molecular medicine · 2023 · 8 claims · 8 setups
β-catenin binds directly to promoters of RNA processing, splicing, and ribosomal biogenesis genes in T-ALL cells
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Full-text index only
Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardation.
PMID 17704778 · PMC2872770 · Nature genetics · 2007 · 8 claims · 6 setups
Mutations in UPF3B cause syndromic (Lujan-Fryns syndrome, FG syndrome) and nonsyndromic X-linked mental retardation
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Full-text index only
Genomics of signaling crosstalk of estrogen receptor alpha in breast cancer cells.
PMID 18365014 · PMC2268000 · PloS one · 2008 · 7 claims · 6 setups
Estrogen, growth factors and cAMP elicit surprisingly distinct ERα-dependent transcriptional responses in MCF7 cells
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Has reproduction · 81
Ribosome A and P sites revealed by length analysis of ribosome profiling data.
PMID 25805170 · PMC4402525 · Nucleic acids research · 2015 · 8 claims · 8 setups
Accounting for ribosome footprint length variation reveals the ribosome aminoacyl (A) and peptidyl (P) site locations within footprints.
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Has reproduction · 90
Evolutionary repair: Changes in multiple functional modules allow meiotic cohesin to support mitosis.
PMID 32155147 · PMC7138332 · PLoS biology · 2020 · 8 claims · 8 setups
Replacing the mitotic kleisin Scc1 with the meiotic kleisin Rec8 impairs sister chromosome cohesion, advances genome replication timing, and reduces reproductive fitness by 45%.