Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 5

System / cell line: cd11b+ ✕ Assay: cytokine ✕ Clear

Indigenous gut microbes modulate neural cell state and neurodegenerative disease susceptibility.

PMID 41638211 · PMC13091097 · Cell systems · 2026 · 8 claims · 7 setups

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A complex, intact gut microbiome is necessary for the steady-state transcriptional landscape of all major brain-resident cell types, with myelinating oligodendrocytes and immune cells showing the largest microbiome-dependent transcriptional response.

hippocampus cd11b+ intestinal brain single-nucleus bulk multiplex
Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs.

PMID 41770903 · PMC13078882 · The Journal of clinical investigation · 2026 · 8 claims · 8 setups

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A commensal Ascomycota fungus, Engyodontium sp., was isolated live from mouse feces using a Dectin-2-Fc fusion protein

feces colonic colon ncm460 its flow qpcr
Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo.

PMID 18651708 · PMC2699546 · Proteomics · 2008 · 8 claims · 6 setups

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A dermis-based cell-trapped system (DBCTS) with human sebocytes inserted into a subcutaneous tissue chamber creates a humanized acne microenvironment in mice

chamber infiltrated de-epidermized sebocyte cfu sandwich immunofluorescence
Loss of CD4(+) T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.

PMID 37572656 · PMC10576612 · Immunity · 2023 · 8 claims · 8 setups

Has reproduction · 68

Arg1 is highly and specifically induced in lung CD4+ T cells during in vivo influenza infection

flow-sort-purified lung cd4+ congenically rna-seq flow expression
CLK1 Promotes Myeloid-Derived Suppressor Cell Trafficking and Reprograms the Tumor Microenvironment by Activating Hippo/YAP Signaling in Colorectal Cancer.

PMID 41686262 · PMC13136879 · Cancer immunology research · 2026 · 8 claims · 8 setups

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CLK1 is markedly upregulated in immune-cold colorectal tumors and correlates with increased MDSC infiltration and CD8+ T-cell exclusion

colorectal tcga-coad ct26 tumor scrna-seq bulk multiplex

Experiments

Indigenous gut microbes modulate neural cell state and neurodegenerative disease susceptibility.

Colonic Engyodontium fungus triggers neutrophil antimicrobial activity to suppress Lactobacillus johnsonii-derived glutamic acid-maintained Tregs.

Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo.

Loss of CD4(+) T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection.

CLK1 Promotes Myeloid-Derived Suppressor Cell Trafficking and Reprograms the Tumor Microenvironment by Activating Hippo/YAP Signaling in Colorectal Cancer.