Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity.
PMID 41951591 · PMC13237135 · Nature communications · 2026 · 8 claims · 8 setups
RPT2 domain missense mutations disrupt SMARCB1 antiproliferative function by destabilizing the SWI/SNF complex and impairing chromatin remodeling and transcriptional regulation, comparable to nonsense mutations
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Mutational landscape and molecular bases of echinocandin resistance in Saccharomyces cerevisiae.
PMID 41766466 · PMC13147539 · Genetics · 2026 · 8 claims · 5 setups
The three echinocandin resistance hotspots of Fks1 form a single, solvent-exposed, water-filled binding cavity spanning hotspot 1, 2, and 3