Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Comparing the utility of in vivo transposon mutagenesis approaches in yeast species to infer gene essentiality.

  PMID 32681306 · PMC7599172 · Current genetics · 2020 · 7 claims · 7 setups

  Has reproduction · 81

  A Random Forest machine-learning approach can predict gene essentiality from in vivo transposon insertion data across multiple yeast species and transposon systems

  cerevisiae pombe albicans hermes acds piggybac

• Estimation of peptide elongation times from ribosome profiling spectra.

  PMID 33885812 · PMC8136808 · Nucleic acids research · 2021 · 8 claims · 3 setups

  Has reproduction · 76

  A maximum-likelihood model that separates context-dependent bias factors from elongation-time factors enables bias-corrected estimation of peptide elongation times at single-codon resolution from Ribo-Seq spectra.

  coli saccharomyces ribosome

• The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.

  PMID 30899024 · PMC6428865 · Nature communications · 2019 · 7 claims · 8 setups

  Has reproduction · 85

  Xrn1 promotes translation of a specific group of mRNAs encoding membrane/secretome proteins, acting at translation initiation.

  cerevisiae yeast xrn1∆ western luciferase polysome