Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 84
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
PMID 35013236 · PMC8748982 · Nature communications · 2022 · 8 claims · 8 setups
Aβ (APP/PS1) and Tau (MAPT P301S) pathology induce distinct but overlapping astrocyte translatome signatures
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Has reproduction · 56
Modulation of HERV Expression by Four Different Encephalitic Arboviruses during Infection of Human Primary Astrocytes.
PMID 36423114 · PMC9694637 · Viruses · 2022 · 6 claims · 7 setups
The four arboviruses commonly induce upregulation of HERVs in human primary astrocytes, with 15 HERVs co-modulated by all four viruses, including highly upregulated HERV4_4q22.1
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Gene expression profiles of HIV-1-infected glia and brain: toward better understanding of the role of astrocytes in HIV-1-associated neurocognitive disorders.
PMID 19697136 · PMC3107560 · Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2010 · 8 claims · 6 setups
Astrocyte gene expression dysregulation resulting from HIV-1 exposure may contribute to HIV-1 neuropathogenesis
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The use of neuroproteomics in drug abuse research.
PMID 19926406 · PMC3947580 · Drug and alcohol dependence · 2010 · 8 claims · 8 setups
Neuroproteomic technologies (2D-DIGE, iTRAQ, ICAT, etc.) enable identification of protein-level changes underlying effects of drugs of abuse such as amphetamine, morphine, cocaine, and alcohol.