Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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L2L: a simple tool for discovering the hidden significance in microarray expression data.
PMID 16168088 · PMC1242216 · Genome biology · 2005 · 8 claims · 4 setups
L2L systematically compares a user's differentially expressed gene list against a database of published differentially expressed gene lists to find statistically significant overlaps and generate hypotheses about shared mechanisms
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Quantitative mass spectrometry of diabetic kidney tubules identifies GRAP as a novel regulator of TGF-beta signaling.
PMID 19836472 · PMC2829334 · Biochimica et biophysica acta · 2010 · 8 claims · 7 setups
Label-free 2D-LC-MS/MS quantitative proteomics identified 476 significantly differentially expressed proteins in kidney tubules of diabetic OVE26 mice versus control mice
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Localized-statistical quantification of human serum proteome associated with type 2 diabetes.
PMID 18795103 · PMC2529402 · PloS one · 2008 · 8 claims · 5 setups
Developed LSPAD (localized statistics of protein abundance distribution) to calculate statistical significance of protein-abundance bias between two serum cohorts using a local Fisher's exact test window
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Has reproduction
D2H2: diabetes data and hypothesis hub.
PMID 38107655 · PMC10723036 · Bioinformatics advances · 2023 · 6 claims · 5 setups
D2H2 is a web portal hosting hundreds of curated, uniformly reprocessed diabetes-relevant transcriptomics datasets from GEO with per-study visualization, differential expression, and single-gene queries.
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Has reproduction · 89
Identification of potential therapeutic targets for nonischemic cardiomyopathy in European ancestry: an integrated multiomics analysis.
PMID 39267096 · PMC11396958 · Cardiovascular diabetology · 2024 · 8 claims · 7 setups
Two-sample MR analysis identified 255 circulating plasma proteins associated with NISCM
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Has reproduction · 78
Requirements for Pseudomonas aeruginosa acute burn and chronic surgical wound infection.
PMID 25057820 · PMC4109851 · PLoS genetics · 2014 · 8 claims · 8 setups
In vivo gene expression is generally not correlated with a gene's importance for fitness, with the exception of metabolic genes, for which differential expression is more predictive of fitness.
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BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments.
PMID 16845052 · PMC1538844 · Nucleic acids research · 2006 · 8 claims · 8 setups
Babelomics is presented as an updated, complete suite of web tools for functional analysis of genome-scale experiments with new and improved modules
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[Research progress in SELDI-TOF MS and its clinical applications].
PMID 17168305 · PMC7148935 · Sheng wu gong cheng xue bao = Chinese journal of biotechnology · 2006 · 4 claims · 4 setups
Proteinchip profiling based on SELDI-TOF MS is a powerful and innovative proteomic technology for biomarker discovery and diagnostic/prognostic assay development.