Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 75
Cross-species comparative hippocampal transcriptomics in Alzheimer's disease.
PMID 38292167 · PMC10824791 · iScience · 2024 · 8 claims · 8 setups
The three mouse models (5xFAD, APP/PS1, hAβ-KI) share more DEGs and GOBP terms with LOAD than with EOAD patients
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Single-cell atlas of the developing Down syndrome brain cortex.
PMID 41545595 · PMC13004680 · Nature medicine · 2026 · 8 claims · 8 setups
RORB/FOXP1-expressing L4-like excitatory neurons are subtype-specifically and dramatically reduced in Down syndrome fetal cortex, especially at later stages (PCW16-20)
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Splicing variants in MYRF cause partial loss of function in the retinal pigment epithelium leading to nanophthalmos.
PMID 41746734 · PMC13043084 · JCI insight · 2026 · 8 claims · 8 setups
The dG-MYRF C-terminal frameshift variant undergoes normal homotrimerization, cleavage, and nuclear localization but shows reduced steady-state levels of the C-terminal cleavage product and decreased transcriptional activation of target genes.
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Ectopic CD11c Drives SMAD3-Mediated Aberrant Antigen Presentation and Epithelial-Mesenchymal Transition in Esophageal Squamous Cell Carcinoma.
PMID 41799568 · PMC12963642 · Cancer communications (London, England) · 2026 · 8 claims · 13 setups
An ESCC epithelial cell subcluster with ectopic CD11c (ITGAX) expression, found in both mice and humans, exhibits concurrent impaired antigen presentation and EMT phenotypes