Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Probing the cancer genome.
PMID 18492227 · PMC2441462 · Genome biology · 2008 · 8 claims · 8 setups
Combined Sanger and 454 pyrosequencing of MCF-7 BAC clones identified 157 PCR-confirmed translocation breakpoint junctions, including 10 in-frame junctions confirmed at the transcript level
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Future possibilities in the prevention of breast cancer: intervention strategies in BRCA1 and BRCA2 mutation carriers.
PMID 11250722 · PMC138789 · Breast cancer research : BCR · 2000 · 8 claims · 8 setups
BRCA1 and BRCA2 mutations confer an 80-85% lifetime risk (by age 80) of female breast cancer
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DNA methylation analysis by digital bisulfite genomic sequencing and digital MethyLight.
PMID 18628296 · PMC2504308 · Nucleic acids research · 2008 · 8 claims · 6 setups
Digital PCR compartmentalizes individual bisulfite-converted DNA template molecules into separate wells, enabling single-molecule DNA methylation analysis
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The development of an integrated platform to identify breast cancer glycoproteome changes in human serum.
PMID 19782370 · PMC4142217 · Journal of chromatography. A · 2010 · 8 claims · 6 setups
M-LAC (multi-lectin affinity chromatography combining Con A, WGA and Jacalin) provides comprehensive capture of glycoproteins from biological fluids based on differing glycan specificities
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Getting it right: being smarter about clinical trials.
PMID 16608383 · PMC1435786 · PLoS medicine · 2006 · 9 claims · 8 setups
Bias and confounding in observational studies can produce misleading associations that are overturned by randomized trials (e.g., HRT).