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High-fidelity bidirectional translation between single-cell transcriptomes and DNA methylomes with scBOND.
PMID 41887797 · PMC13138010 · Genome research · 2026 · 7 claims · 6 setups
scBOND is a bidirectional dual-channel VAE framework for cross-modality translation between scRNA-seq and scDNAm that outperforms existing baseline methods (scCross, MAPLE) in both translation directions