Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 14

System / cell line: cd3+ ✕ Assay: disease ✕ Clear

Distinct phenotypes and repertoires of bronchoalveolar and airway mucosal T cells in health and allergic asthma.

PMID 41519381 · PMC12983186 · Mucosal immunology · 2026 · 8 claims · 6 setups

Full-text index only

BAL and endobronchial brush sampling capture phenotypically and clonally distinct T cell populations

sorted paired bal subjects single-cell fluorescence-activated methacholine
singIST: An integrative method for comparative single-cell transcriptomics between disease models and humans.

PMID 41838773 · PMC13008255 · PLoS computational biology · 2026 · 8 claims · 7 setups

Full-text index only

singIST provides explainable quantitative measures of disease model similarity to a human reference at the pathway, cell type, and gene levels

skin ear simulated scrna-seq simulation
Immunosuppressive contribution of tumour-infiltrating B cells in human intrahepatic cholangiocarcinoma and their role in chemoimmunotherapy outcome.

PMID 40889886 · PMC13217081 · Gut · 2026 · 8 claims · 7 setups

Full-text index only

High density of CD20+ B cells in the peritumoural area is associated with improved disease-free survival in iCCA

resected cd45+ scrna-seq peripheral immunohistochemistry kaplan-meier scrna-seq
RNA Editing Alterations Define Disease Manifestations in the Progression of Experimental Autoimmune Encephalomyelitis (EAE).

PMID 36429012 · PMC9688714 · Cells · 2022 · 7 claims · 7 setups

Has reproduction · 37

RNA-editing events mediated by APOBEC and ADAR deaminases are significantly reduced throughout the course of EAE disease progression

brain rna-edited brain-isolated naïve rna-seq pathway pcr
Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion.

PMID 19097825 · PMC2692687 · Clinical immunology (Orlando, Fla.) · 2009 · 8 claims · 7 setups

Full-text index only

CORO1A deficiency, caused by a paternal 2bp frameshift mutation combined with a maternal de novo 600kb deletion at chromosome 16p11.2, is the molecular cause of this patient's T-B+NK+ SCID

ebv-transformed genomic father peripheral intracellular snp sequencing
Development of a pediatric immune cell atlas and characterization of CD4+ T cells in food allergy.

PMID 42025535 · PMC13105851 · Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026 · 8 claims · 8 setups

Full-text index only

A pediatric single-cell PBMC reference atlas was developed from 57 healthy children across 8 public scRNA-seq studies.

pbmcs cd3+ cd4+ memory scrna-seq pseudobulk bulk
Inflammatory Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma: Transcriptional Signature and In Vitro Modeling.

PMID 37958322 · PMC10650304 · Cancers · 2023 · 8 claims · 8 setups

Has reproduction · 50

A 279-gene 'iMSC signature' is upregulated in BM MSCs from MM patients compared to healthy donors, identified by reanalysis of single-cell RNA-seq data.

facs-isolated expanded bm-mscs mscs single-cell bulk gene
Single-immunocyte transcriptomics reveal the role of natural killer cell-dependent exogenous antigen presentation in ankylosing spondylitis severity.

PMID 41593306 · PMC12868835 · Experimental & molecular medicine · 2026 · 8 claims · 8 setups

Full-text index only

Innate antibacterial defense functions are generally enhanced in most cell types at AS onset and are negatively associated with AS severity

pbmcs gwas pbmc-derived cd4+ single-cell bulk mendelian
Gene regulatory network determinants of rapid recall in human memory CD4(+) T cells.

PMID 41865369 · PMC13207208 · Cell reports · 2026 · 8 claims · 6 setups

Full-text index only

Memory CD4+ T cells show enhanced chromatin accessibility proximal to rapid-recall genes compared to naive cells

blood-derived computational pseudobulk cd4+ single-nuclei maxatac grn
The liver as an immunological barrier redefined by single-cell analysis.

PMID 32176810 · PMC7218664 · Immunology · 2020 · 8 claims · 8 setups

Has reproduction · 100

Emerging single-cell technologies have advanced or redefined understanding of the liver's immunological barrier function

liver c57bl sorted pdgfrb-gfp scrna-seq single-molecule
Clonal CD8(+) T cells populate the leptomeninges and coordinate with immune cells in human degenerative brain diseases.

PMID 41593242 · PMC12864034 · Nature immunology · 2026 · 8 claims · 6 setups

Full-text index only

The human leptomeninges harbor substantial numbers of clonally expanded, tissue-resident memory CD8 T cells (ZNF683-high, CXCR6+, PD-1+)

postmortem leptomeninges scrna-seq-derived leptomeningeal single-cell flow imaging
Intestinal macrophages modulate synucleinopathy along the gut-brain axis.

PMID 41606336 · PMC12960212 · Nature · 2026 · 8 claims · 8 setups

Full-text index only

ME-Macs engulf misfolded, aggregated αS and modulate αS pathology and neurodegeneration in PD mouse models

3kl sorted me-macs snca immunohistochemistry digital mass
Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma.

PMID 41882179 · PMC13035477 · Nature cancer · 2026 · 8 claims · 8 setups

Full-text index only

LN-resident stromal cells (FRCs, BECs, LECs) drive chemokine-based lymphocyte zonation, and disruption of this system underlies the loss of tissue organization in nodal B cell lymphoma

rln healthy bulk fl-ln scrna-seq multiplex bulk
Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils.

PMID 38358352 · PMC10903300 · Cancer research communications · 2024 · 8 claims · 7 setups

Has reproduction · 64

Two main neutrophil subtypes exist in primary tumors: an activated subtype sharing transcriptomic signatures with healthy neutrophils, and a tumor-specific subtype.

colorectal sorted integrated neutrophil scrna-seq bulk immunohistochemistry

Experiments

Distinct phenotypes and repertoires of bronchoalveolar and airway mucosal T cells in health and allergic asthma.

singIST: An integrative method for comparative single-cell transcriptomics between disease models and humans.

Immunosuppressive contribution of tumour-infiltrating B cells in human intrahepatic cholangiocarcinoma and their role in chemoimmunotherapy outcome.

RNA Editing Alterations Define Disease Manifestations in the Progression of Experimental Autoimmune Encephalomyelitis (EAE).

Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion.

Development of a pediatric immune cell atlas and characterization of CD4+ T cells in food allergy.

Inflammatory Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma: Transcriptional Signature and In Vitro Modeling.

Single-immunocyte transcriptomics reveal the role of natural killer cell-dependent exogenous antigen presentation in ankylosing spondylitis severity.

Gene regulatory network determinants of rapid recall in human memory CD4(+) T cells.

The liver as an immunological barrier redefined by single-cell analysis.

Clonal CD8(+) T cells populate the leptomeninges and coordinate with immune cells in human degenerative brain diseases.

Intestinal macrophages modulate synucleinopathy along the gut-brain axis.

Reprogramming of stroma-derived chemokine networks drives the loss of tissue organization in nodal B cell lymphoma.

Characterizing Neutrophil Subtypes in Cancer Using scRNA Sequencing Demonstrates the Importance of IL1β/CXCR2 Axis in Generation of Metastasis-specific Neutrophils.