Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
-
Full-text index only
NMR solution structure of the major G-quadruplex structure formed in the human BCL2 promoter region.
PMID 16998187 · PMC1636422 · Nucleic acids research · 2006 · 8 claims · 8 setups
The major BCL2 promoter G-quadruplex (bcl2Mid) is a well-defined, mixed parallel/antiparallel-stranded intramolecular structure with three G-tetrads, two lateral loops, one side loop, and four grooves of different widths
-
Full-text index only
Detection of rare mutant K-ras DNA in a single-tube reaction using peptide nucleic acid as both PCR clamp and sensor probe.
PMID 16432256 · PMC1345699 · Nucleic acids research · 2006 · 8 claims · 5 setups
A 17mer PNA spanning K-ras codons 12/13 can serve as both PCR clamp and sensor probe in a single-tube reaction, differentiating all 12 possible point mutations from wild-type by melting temperature shift
-
Full-text index only
In silico segmentations of lentivirus envelope sequences.
PMID 17376229 · PMC1847453 · BMC bioinformatics · 2007 · 8 claims · 8 setups
C and V regions of lentivirus SU sequences have distinct statistical (oligonucleotide/amino-acid) compositions that HMMs can learn and use to delimit them.
-
Full-text index only
Net positive charge of HIV-1 CRF01_AE V3 sequence regulates viral sensitivity to humoral immunity.
PMID 18787705 · PMC2527523 · PloS one · 2008 · 8 claims · 5 setups
Reduction in V3's net positive charge makes V3 less variable due to limited positive selection