Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 79
Genome-wide prediction of DNase I hypersensitivity using gene expression.
PMID 29051481 · PMC5715040 · Nature communications · 2017 · 8 claims · 5 setups
Gene expression can, to a large extent, predict genome-wide DNase I hypersensitivity (chromatin accessibility)
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Optimized library preparation, sequencing, and data analysis protocols for the generation of orbivirus consensus sequences.
PMID 41527034 · PMC12809950 · BMC genomics · 2026 · 8 claims · 8 setups
Optimized sample and library preparation protocols achieved comparable results to established methods while requiring simpler sample preparation.
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ChromBERT: A foundation model for learning interpretable representations for context-specific transcriptional regulatory networks.
PMID 41592570 · PMC13069865 · Cell genomics · 2026 · 8 claims · 7 setups
ChromBERT is pre-trained via masked reconstruction on the Cistrome-Human-6K dataset (6,391 cistromes, 991 transcription regulators) to learn genome-wide interaction syntax of transcription regulators
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CLAMP: predicting specific protein-mediated chromatin loops in diverse species with a chromatin accessibility language model.
PMID 41555433 · PMC12903630 · Genome biology · 2026 · 8 claims · 8 setups
CLAMP, a chromatin-accessibility language model, predicts protein-mediated chromatin loops across 10 species, 18 proteins, and 24 cell types with superior performance versus existing methods.
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The two faces of Alba: the evolutionary connection between proteins participating in chromatin structure and RNA metabolism.
PMID 14519199 · PMC328453 · Genome biology · 2003 · 8 claims · 5 setups
Sequence-profile (PSI-BLAST) searches unify archaeal Alba with eukaryotic RNase P/MRP subunits Rpp20/Pop7 and Rpp25, and with the ciliate macronuclear-development protein Mdp2, into a single Alba superfamily.
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Atlas of nascent RNA transcripts reveals tissue-specific enhancer to gene linkages.
PMID 40281430 · PMC12032694 · BMC genomics · 2025 · 7 claims · 8 setups
A large repository of nascent run-on RNA-seq samples (DBNascent) was assembled and uniformly processed to identify sites of bidirectional transcription genome-wide.
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In silico meets in vivo.
PMID 18304380 · PMC2374716 · Genome biology · 2008 · 8 claims · 8 setups
About 10% of positions in multiple sequence alignments of the human genome with other vertebrate genomes are likely incorrect.
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Has reproduction
Methylation patterns of the nasal epigenome of hospitalized SARS-CoV-2 positive patients reveal insights into molecular mechanisms of COVID-19.
PMID 40170038 · PMC11963311 · BMC medical genomics · 2025 · 7 claims · 7 setups
Differential DNA methylation occurs predominantly in intergenic regions and low methylated regions (LMRs), highlighting the role of distal regulatory elements in COVID-19 severity.
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Has reproduction · 85
Ensembl 2013.
PMID 23203987 · PMC3531136 · Nucleic acids research · 2013 · 8 claims · 8 setups
Ensembl (http://www.ensembl.org) provides genome information for sequenced chordate genomes, currently supporting 70 species with a focus on human, mouse, zebrafish and rat.