Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Benchmarking RNA velocity methods across 17 independent studies.

  PMID 41916302 · PMC13106975 · Cell reports methods · 2026 · 8 claims · 6 setups

  Full-text index only

  No single RNA velocity method exhibited superior performance across all accuracy, stability, and usability assessments

  scrna-seq same representative dyngen-simulated velocity cross-method downsampling

• Cell neighborhood topology directs rare cell population identification.

  PMID 41912521 · PMC13199379 · Nature communications · 2026 · 8 claims · 8 setups

  Full-text index only

  RareQ is a framework that quantifies neighborhood connectivity (Q), a cell-specific measure of kNN-graph cliquishness, to detect rare cell populations from single-cell and spatial omics data

  downsampled pbmc brain simulated scrna-seq cite-seq single-cell

• Hi-Compass: a depth-aware deep learning framework for predicting cell-type-specific 3D genome organization from single-cell to spatial resolution.

  PMID 41980945 · PMC13250166 · Nature communications · 2026 · 8 claims · 8 setups

  Full-text index only

  Hi-Compass predicts cell-type-specific Hi-C contact maps using only ATAC-seq as cell-type-specific input, plus DNA sequence and a generalized CTCF binding profile

  gm12878 curated bulk training hi-c ctcf matched

• ANOMALY: a Snakemake pipeline for identifying NuMTs from long-read sequencing data.

  PMID 41647924 · PMC12869244 · NAR genomics and bioinformatics · 2026 · 8 claims · 8 setups

  Full-text index only

  ANOMALY is a novel Snakemake pipeline for detecting NuMTs from long-read sequencing data

  simulated real-world matched long-read short-read pipeline

• SnakeAltPromoter Facilitates Differential Alternative Promoter Analysis.

  PMID 41993886 · PMC13082578 · Computational and structural biotechnology journal · 2026 · 6 claims · 6 setups

  Full-text index only

  SnakeAltPromoter is the first unified, reproducible Snakemake workflow that automates alternative promoter analysis from raw RNA-seq data using 3 complementary methods (ProActiv, Salmon, DEXSeq)

  heart brain gm12878 simulated bulk cage rna-seq

• Evaluating imputation methods for accurate estimation of cell population fractions in single-cell RNA sequencing.

  PMID 41503159 · PMC12770975 · NAR genomics and bioinformatics · 2026 · 8 claims · 6 setups

  Full-text index only

  Eight prominent imputation methods (MAGIC, SAVER, scVI, DCA, scBiG, kNN-smoothing, scImpute, ALRA) were systematically evaluated for their ability to recover the true non-zero expression fraction using simulated and real-world scRNA-seq data

  basal tracheal airway k562 simulated scrna-seq imputation

• Whole-genome sequencing with AVITI and NovaSeq X Plus reveals comparable performance with contextual biases.

  PMID 42206012 · PMC13202175 · NAR genomics and bioinformatics · 2026 · 8 claims · 7 setups

  Full-text index only

  AVITI and NovaSeq X Plus are highly comparable overall for variant-calling performance in WGS

  tumor mm1s aviti chr20 whole-genome pacbio small

• Resolving clonal evolution and selection of extrachromosomal DNA at single-cell resolution.

  PMID 41606654 · PMC12853921 · Genome biology · 2026 · 7 claims · 8 setups

  Full-text index only

  ecSingle, a computational method integrating allelic imbalance (BAF deviation) and outlier expression from scRNA-seq, can identify oncogene-carrying ecDNA at single-cell resolution.

  colo320dm glioblastoma medulloblastoma ce26 scrna-seq whole-genome long-read