Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Manual validation finds ultra-long-read sequencing best enables faithful, population-level structural variant calling in Drosophila melanogaster euchromatin with nanopore.
PMID 41806374 · PMC13148403 · G3 (Bethesda, Md.) · 2026 · 8 claims · 5 setups
Only ultra-long long-reads (N50 > 50 kb) are capable of accurately calling structural variants of any size in D. melanogaster euchromatin
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Has reproduction · 78
Single duplex DNA sequencing with CODEC detects mutations with high sensitivity.
PMID 37106072 · PMC10181940 · Nature genetics · 2023 · 8 claims · 8 setups
CODEC concatenates both strands of an original DNA duplex into a single NGS read pair via an adapter quadruplex and strand-displacing extension, enabling single-duplex resolution
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Whole-genome sequencing with AVITI and NovaSeq X Plus reveals comparable performance with contextual biases.
PMID 42206012 · PMC13202175 · NAR genomics and bioinformatics · 2026 · 8 claims · 7 setups
AVITI and NovaSeq X Plus are highly comparable overall for variant-calling performance in WGS
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Sensitive detection of somatic mutations in GC-rich cancer gene promoters.
PMID 42088607 · PMC13136893 · NAR cancer · 2026 · 8 claims · 8 setups
Gene promoters, due to high GC content (CpG islands, ~70% of promoters), are systematically undersampled and have poor coverage in whole cancer genomes, causing missed somatic mutation calls