Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Undergraduate research. Genomics Education Partnership.
PMID 18974335 · PMC2953277 · Science (New York, N.Y.) · 2008 · 6 claims · 4 setups
A course-embedded, multi-institution undergraduate research model (the Genomics Education Partnership) can deliver authentic research experiences during the academic year rather than only in summer programs.
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Has reproduction · 61
TEMP: a computational method for analyzing transposable element polymorphism in populations.
PMID 24753423 · PMC4066757 · Nucleic acids research · 2014 · 8 claims · 8 setups
TEMP combines pair-end (discordant) read and split (soft-clipped) read information to identify both presence and absence of TE insertions in genomic DNA from heterogeneous/pooled samples.
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From linear genome sequence to three-dimensional organization of the cell nucleus.
PMID 12620101 · PMC153456 · Genome biology · 2003 · 8 claims · 8 setups
Chromosome conformation capture (3C) can quantify in vivo physical interaction frequencies between genomic loci by crosslinking, digestion, and intramolecular ligation followed by PCR
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Charting the map of life.
PMID 11171541 · PMC1242061 · Environmental health perspectives · 2001 · 8 claims · 8 setups
Only 3-5% of the human genome, corresponding to 30,000-100,000 genes, is thought to be biologically functional
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The revolution of the biology of the genome.
PMID 15040884 · PMC7091781 · Cell research · 2004 · 8 claims · 6 setups
Polyploidization and gene duplication are the major mechanisms increasing eukaryotic genome size.
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Mining the draft human genome.
PMID 11236999 · PMC2658632 · Nature · 2001 · 8 claims · 7 setups
Protein-coding exons account for only about 3% of the human genome DNA, with repeat sequences making up around 46%.
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Versatile and open software for comparing large genomes.
PMID 14759262 · PMC395750 · Genome biology · 2004 · 8 claims · 8 setups
MUMmer 3.0 efficiently handles comparisons of large eukaryotic genomes at varying evolutionary distances
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Identifying cis-regulatory sequences by word profile similarity.
PMID 19730735 · PMC2731932 · PloS one · 2009 · 8 claims · 8 setups
WPH-finder identifies putative co-regulated CRMs by scanning the genome for sequences with word profiles similar to a known CRM, without explicitly defining binding sites
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Sequencing the regulatory genome.
PMID 18598374 · PMC2481419 · Genome biology · 2008 · 8 claims · 8 setups
Nuclear-lamina-associated domains (LADs) define chromatin regions with distinct transcriptional characteristics (fewer, lower-expressed genes, low RNA Pol II occupancy, H3K27me3-enriched borders)
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GenBank.
PMID 16381837 · PMC1347519 · Nucleic acids research · 2006 · 8 claims · 8 setups
GenBank is a comprehensive public database of nucleotide sequences with supporting bibliographic and biological annotation, built and distributed by NCBI.
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Automatic annotation of eukaryotic genes, pseudogenes and promoters.
PMID 16925832 · PMC1810547 · Genome biology · 2006 · 8 claims · 6 setups
Fgenesh++ gene prediction pipeline identifies 91% of coding nucleotides with 90% specificity
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The many uses of a genome sequence.
PMID 11423005 · PMC138940 · Genome biology · 2001 · 8 claims · 8 setups
Solved protein structures from structural genomics efforts can be used to model many other proteins by homology, aiding function prediction