Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Berberine suppresses colon inflammation via integrated modulation of host metabolism, microbial ecology, and innate immune signaling.
PMID 41356191 · PMC12680593 · Theranostics · 2026 · 6 claims · 8 setups
Berberine enhances energy metabolism (oxidative phosphorylation, ATP biosynthesis, fatty acid metabolism) in intestinal epithelial cells of DSS-induced mice, preserving normal physiological function
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Has reproduction · 69
Integrative analysis of single-cell RNA-seq and gut microbiome metabarcoding data elucidates macrophage dysfunction in mice with DSS-induced ulcerative colitis.
PMID 38879692 · PMC11180211 · Communications biology · 2024 · 7 claims · 7 setups
Epithelial cell populations are significantly reduced during acute DSS colitis, reflecting tissue damage, with partial recovery in chronic colitis
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The transcription factor EHF promotes the maturation and immunosuppression of conventional dendritic cells.
PMID 41730908 · PMC13039115 · Nature communications · 2026 · 8 claims · 8 setups
EHF orchestrates an immunosuppressive maturation program in cDC1s and cDC2s downstream of TLR7/8/9 sensing of self-nucleic acids
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Microbiota-derived IPA protects against colitis by regulating intestinal HMGCS2-mediated ketogenesis to facilitate mucosal healing.
PMID 41651833 · PMC12988232 · Nature communications · 2026 · 8 claims · 8 setups
IPA is consistently depleted in IBD/colitis patients and in murine colitis models relative to healthy controls