Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Structural genomics of membrane proteins.
PMID 15059248 · PMC395774 · Genome biology · 2004 · 9 claims · 8 setups
Membrane proteins comprise less than 1 in 100 of structures deposited in the Protein Data Bank despite being a large fraction of the proteome.
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Has reproduction · 94
Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials.
PMID 33558569 · PMC7870661 · Scientific data · 2021 · 8 claims · 6 setups
A unified, easily accessible, reusable collection of ENM transcriptomics data was lacking prior to this work despite large amounts of existing data
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HIT: a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular proteins and surface molecules.
PMID 18849997 · PMC3334282 · Nature medicine · 2008 · 8 claims · 8 setups
HIT uses oligonucleotide-tagged (Fab- or mSA-conjugated) antibodies, T7 polymerase amplification, and DNA microarray hybridization to indirectly measure multiple analytes in a fluid-phase multiplex format
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Comparing protein abundance and mRNA expression levels on a genomic scale.
PMID 12952525 · PMC193646 · Genome biology · 2003 · 8 claims · 8 setups
Correlations between mRNA expression and protein abundance are generally poor or limited across most studies reviewed, including in yeast and human cancers