Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo.

  PMID 35784648 · PMC9243631 · Cell reports methods · 2022 · 8 claims · 7 setups

  Has reproduction · 66

  A purification-free hyperTRIBE method (FMR1-ADARcd-V5) can identify stress granule RNAs in bulk and single Drosophila S2 cells and in Drosophila neurons

  fmr1-adarcd-v5 single bioinformatic drosophila immunofluorescence western bulk

• Editing of hnRNP K protein mRNA in colorectal adenocarcinoma and surrounding mucosa.

  PMID 16404425 · PMC2361188 · British journal of cancer · 2006 · 7 claims · 8 setups

  Full-text index only

  A G274A base substitution in hnRNP K mRNA is present in colorectal tumours and surrounding mucosa but absent from corresponding genomic DNA, indicating an RNA editing event rather than a germline polymorphism.

  colorectal cdna matched thyroid rt-pcr restriction genomic

• Manipulation of Alternative Splicing of IKZF1 Elicits Distinct Gene Regulatory Responses in T Cells.

  PMID 41677588 · PMC12896614 · Cells · 2026 · 8 claims · 6 setups

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  Alternative splicing of IKZF1 in human T cells strongly influences gene expression, chromatin accessibility, and protein production.

  jurkat genomic cd4+ rna-seq atac-seq immunoblotting

• Functional correction and genome integrity with duplex base editing of β-thalassemic hematopoietic stem cells.

  PMID 41629994 · PMC12952134 · Genome biology · 2026 · 8 claims · 8 setups

  Full-text index only

  Duplex base editing (2×BE) of BCL11A enhancer and HBG promoter produces significantly higher HbF and γ-globin induction than simplex BE or DSB-Cas9 editing

  β-thalassemic clones sanger ice targeted

• GLYATL1 is associated with metabolic and epigenetic changes and with endocrine resistance in luminal breast cancer.

  PMID 42050691 · PMC13126711 · Clinical epigenetics · 2026 · 8 claims · 8 setups

  Full-text index only

  GLYATL1 expression is upregulated in AI-resistant breast cancer cell models and in patients undergoing AI therapy

  mcf7 lysates rna-sequencing atac-sequencing epic

• CHD7 regulates otic lineage specification and hair cell differentiation in human inner ear organoids.

  PMID 36396635 · PMC9672366 · Nature communications · 2022 · 8 claims · 8 setups

  Has reproduction · 50

  Loss of CHD7 or its ATP-dependent chromatin remodeling activity causes complete absence of hair cells and supporting cells in inner ear organoids

  inner facs-isolated hescs hesc immunostaining scrna-seq western