Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Disruption of metabolic licensing by JAK inhibitors constrains CD8 T cell activation and effector function.

  PMID 41876467 · PMC13039990 · Cell death & disease · 2026 · 8 claims · 8 setups

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  JAKis targeting JAK1, JAK1/2, or JAK1/3 markedly reduce CD8 T cell activation markers, proliferation, and effector molecule (TNF, granzyme B) production

  naive memory activated sorted flow scenith cd8

• Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development.

  PMID 41686912 · PMC13015429 · Science immunology · 2026 · 8 claims · 8 setups

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  Efficiency of B cell priming, not complexity of Env-guided affinity maturation, is the primary obstacle to V2 apex bNAb elicitation in SHIV-infected macaques.

  shiv-infected plasma igg+ rhesus plasma single-genome next-generation