Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Tags for labeling protein N-termini with subtiligase for proteomics.
PMID 18762420 · PMC2590642 · Bioorganic & medicinal chemistry letters · 2008 · 6 claims · 4 setups
Arginine-rich peptide esters (3, 4, 5) are markedly more soluble than the original TEVest2 ester (1) and give significantly higher N-terminal tagging of proteins by subtiligase at higher concentrations.
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Proteomic surveillance of retinal autoantigens in endogenous uveitis: implication of esterase D and brain-type creatine kinase as novel autoantigens.
PMID 18552983 · PMC2426731 · Molecular vision · 2008 · 7 claims · 6 setups
Six novel candidate retinal autoantigens (β-actin, esterase D, tubulin β-2, brain-type creatine kinase, VDAC, aspartate aminotransferase) were identified by 2D-WB and mass spectrometry in EAU mice
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Proteomics approaches to identify tumor antigen directed autoantibodies as cancer biomarkers.
PMID 15502247 · PMC3839398 · Disease markers · 2004 · 8 claims · 8 setups
Proteomics approaches (2D Western blot, protein microarray, multiplex ELISA) can identify tumor antigen-directed autoantibodies as candidate cancer biomarkers
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Pre-operative urinary cathepsin D is associated with survival in patients with renal cell carcinoma.
PMID 19789534 · PMC2768081 · British journal of cancer · 2009 · 8 claims · 7 setups
Cathepsin D, identified via comparative 2D PAGE of conditioned media from RCC cell lines vs normal renal cultures, is a candidate secreted biomarker of RCC
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Using proteomic approach to identify tumor-associated antigens as markers in hepatocellular carcinoma.
PMID 18672925 · PMC2680441 · Journal of proteome research · 2008 · 8 claims · 6 setups
34 immunoreactive protein spots were detected in 2DE Western blots probed with HCC patient sera but not normal sera
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Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: accurate detection of CA19-9 levels in pancreatic cancer.
PMID 18615426 · PMC2992687 · Proteomics · 2008 · 8 claims · 6 setups
RPPA-measured CA19-9 levels correlate strongly with ELISA-measured levels in the same patient samples
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Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct characteristics.
PMID 17331236 · PMC1868942 · Genome biology · 2007 · 8 claims · 8 setups
moDCs and KG-1 cells show significant proteomic differences from primary mDCs, particularly in proteins involved in cell growth/maintenance and cell-cell interaction/integrity.
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Endogenous retroviral elements LTR8B and MER65 rewire PSG9 regulation to control trophoblast syncytialization and pre-eclampsia risk.
PMID 41796334 · PMC12969887 · Genome biology · 2026 · 8 claims · 8 setups
LTR8B is a placentally-relevant cis-regulatory element (CRE), notably within the PSG array