Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 65
comBO: A combined human bone and lympho-myeloid bone marrow organoid for preclinical modeling of hematopoietic disorders.
PMID 41734765 · PMC7618947 · Cell stem cell · 2026 · 8 claims · 8 setups
comBO is a single iPSC-derived organoid differentiation that generates osteolineage, vascular, lymphoid, and myeloid compartments together
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Pharmacological perturbation of splicing elicits SMG1 reduction: Implications for cancer therapy.
PMID 41623476 · PMC12857400 · iScience · 2026 · 7 claims · 12 setups
Splicing-modulatory drugs MS023 and indisulam act as inadvertent NMD inhibitors by downregulating SMG1 protein levels
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A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency.
PMID 41649478 · PMC12880805 · eLife · 2026 · 8 claims · 8 setups
Mir195 transduction rescues Ebf1-deficient HPCs, inducing CD19 expression and a B-lineage gene expression program
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A human tumor-immune organoid model of glioblastoma.
PMID 41505256 · PMC12969483 · Cell reports · 2026 · 8 claims · 8 setups
iHOTT is an autologous co-culture platform integrating patient-derived tumor cells and matched PBMCs within human cortical organoids
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Inherited resilience to clonal hematopoiesis by modifying stem cell RNA regulation.
PMID 41477881 · PMC12850507 · Science (New York, N.Y.) · 2026 · 8 claims · 8 setups
A haplotype at the 17q22 locus, tagged by the noncoding variant rs17834140-T, is a causal protective variant against CHIP and myeloid malignancies