Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 68
Targeting the epigenome and the integrated stress response to normalize colorectal cancer subclonal plasticity and progression.
PMID 41963303 · PMC13181133 · Cell death & disease · 2026 · 8 claims · 8 setups
The integrated stress response (ISR) induces CRC cell plasticity, subclonal diversity, and tumor progression in stress-surviving cells
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Has reproduction · 29
CD74 deficiency protects against doxorubicin cardiotoxicity through RRM2-mediated regulation of ferroptosis.
PMID 42180553 · PMC13198236 · Acta pharmaceutica Sinica. B · 2026 · 8 claims · 8 setups
CD74 levels are elevated in plasma of DOX-exposed breast cancer patients and in DOX-challenged mouse hearts and cardiomyocytes
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Has reproduction · 98
Massively parallel genomic perturbations with multi-target CRISPR interrogates Cas9 activity and DNA repair at endogenous sites.
PMID 36064968 · PMC9481459 · Nature cell biology · 2022 · 8 claims · 6 setups
Multi-target gRNAs (mgRNAs) can direct Cas9 to over a hundred well-mapped endogenous genomic sites simultaneously, enabling massively parallel, high-throughput interrogation of Cas9 activity via short-read sequencing
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LINE-1 Locus Transcription Nucleates Oncogenic Chromatin Architecture.
PMID 41489510 · PMC13040219 · Cancer discovery · 2026 · 8 claims · 8 setups
LINE-1 RNAs are primarily chromatin-associated nascent transcripts rather than cytosolic mRNAs