Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• Cell-Type-Specific Gene Modules Related to the Regional Homogeneity of Spontaneous Brain Activity and Their Associations With Common Brain Disorders.

  PMID 33958982 · PMC8093778 · Frontiers in neuroscience · 2021 · 8 claims · 6 setups

  Has reproduction · 59

  Fourteen gene modules were consistently (Bonferroni-corrected) associated with ReHo across a discovery sample and two independent replication samples (including one non-Chinese HCP cohort).

  healthy postmortem ahba neocortex resting-state microarray weighted

• Deconvolution of the hematopoietic stem cell microenvironment reveals a high degree of specialization and conservation.

  PMID 35494238 · PMC9046238 · iScience · 2022 · 7 claims · 7 setups

  Has reproduction · 60

  Integration of three scRNA-seq datasets using a custom bootstrapping-based clustering pipeline robustly identifies 14 endothelial subclusters and 11 mesenchymal (stage-specific) subclusters in mouse bone marrow.

  bone independent scrna-seq gene singler

• Single cell analysis reveals the roles and regulatory mechanisms of type-I interferons in Parkinson's disease.

  PMID 38566100 · PMC10985960 · Cell communication and signaling : CCS · 2024 · 8 claims · 8 setups

  Has reproduction · 55

  Microglia, endothelial cells, and pericytes exhibit the highest IFN-I activity among PD midbrain cell types, with microglia and endothelial cells showing significantly elevated high-IFN-I-scoring proportions in PD versus controls

  midbrain single microglia substantia single-cell scenic monocle

• Science review: searching for gene candidates in acute lung injury.

  PMID 15566614 · PMC1065043 · Critical care (London, England) · 2004 · 8 claims · 8 setups

  Full-text index only

  The candidate gene approach combined with an ortholog gene database and gene ontology analysis identifies ALI candidate genes, with blood coagulation and inflammation ontologies most highly represented

  lung canine pulmonary alveolar microarray gene immunoassay

• Hypoxia-associated genes as predictors of outcomes in gastric cancer: a genomic approach.

  PMID 40129974 · PMC11931070 · Frontiers in immunology · 2025 · 8 claims · 8 setups

  Has reproduction · 96

  A prognostic model built from five H1-specific hypoxia-associated transcription factors (EHF, EIF1AD, GLA, KEAP1, MAGED2) predicts overall survival in STAD, with high-risk patients showing significantly worse OS.

  gastric gene scrna-seq tcga single-cell wgcna cell-cell

• Epigenetic loss of heterogeneity from low to high grade localized prostate tumours.

  PMID 34911933 · PMC8674326 · Nature communications · 2021 · 8 claims · 7 setups

  Has reproduction · 79

  Low-grade (Gleason pattern 3) prostate cancer cells share chromatin accessibility features that are lost in high-grade (Gleason pattern 4) tumours

  flash-frozen tcga single differentially single-cell bulk topic

• Perturbation of placental protein glycosylation by endoplasmic reticulum stress promotes maladaptation of maternal hepatic glucose metabolism.

  PMID 36660474 · PMC9843443 · iScience · 2023 · 8 claims · 8 setups

  Has reproduction · 71

  ER stress reduces the complexity and sialylation of trophoblast protein N-glycosylation

  bewo eif2s1 umbilical placenta maldi-tof western rt-pcr

• Clustering and machine learning-based integration identify cancer associated fibroblasts genes' signature in head and neck squamous cell carcinoma.

  PMID 37065499 · PMC10098459 · Frontiers in genetics · 2023 · 8 claims · 8 setups

  Has reproduction · 63

  Clustering of 31 CAFs genes across 868 HNSCC samples identifies two distinct molecular patterns (C1, C2) with different survival outcomes

  hnscc combined gse164690 tcga-hnsc ssgsea unsupervised immune

• CD14(lo)CD301b(+) macrophages gathering as a proangiogenic marker in adipose tissues.

  PMID 39645040 · PMC11745947 · Journal of lipid research · 2025 · 8 claims · 8 setups

  Has reproduction · 59

  Cd14−/− mice exhibit a leaner body shape and are protected from HFD-induced obesity compared to WT mice

  epididymal adipose cd14low macrophage bulk scrna-seq pseudotime

• iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype.

  PMID 19674965 · PMC2773724 · Molecular & cellular proteomics : MCP · 2009 · 6 claims · 5 setups

  Full-text index only

  Serial transplantation of human GBM xenografts in nude rats converts an initially highly infiltrative, non-angiogenic phenotype into a highly angiogenic phenotype over 4-6 generations.

  membrane-enriched xenograft homogenate quantified itraq western bradford