Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 74
Exploring candidate genes for pericarp russet pigmentation of sand pear (Pyrus pyrifolia) via RNA-Seq data in two genotypes contrasting for pericarp color.
PMID 24400075 · PMC3882208 · PloS one · 2014 · 8 claims · 5 setups
RNA-seq-based bulked segregant analysis of russet- vs green-pericarp F1 pools identified 29,100 unigenes, 206 of which were significantly differentially expressed (|log2 fold change| > 1).
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Has reproduction · 56
Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq.
PMID 34875090 · PMC8887463 · Nucleic acids research · 2022 · 6 claims · 8 setups
Halo-seq pairs a light-activatable Halo-DBF ligand with Click chemistry to label and purify spatially defined RNA populations in living cells with high spatial specificity (~100 nm radius)
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A functional analysis of the CREB signaling pathway using HaloCHIP-chip and high throughput reporter assays.
PMID 19860899 · PMC2774331 · BMC genomics · 2009 · 8 claims · 6 setups
HaloCHIP is a functional antibody-free alternative to ChIP that uses covalent capture of HaloTag-fusion protein-DNA complexes on HaloLink resin
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Headloop suppression PCR and its application to selective amplification of methylated DNA sequences.
PMID 16091627 · PMC1184225 · Nucleic acids research · 2005 · 8 claims · 5 setups
Headloop PCR: a 5' primer extension homologous to internal amplicon sequence causes hairpin formation after incorporation, suppressing further amplification of the matching sequence while unaffected sequences amplify normally