Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Comparative genomics of fungal allergens and epitopes shows widespread distribution of closely related allergen and epitope orthologues.
PMID 17029625 · PMC1613252 · BMC genomics · 2006 · 8 claims · 3 setups
A database of 82 allergen sequences was compiled and used to search 22 fungal genomes for orthologues.
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The specificity and polymorphism of the MHC class I prevents the global adaptation of HIV-1 to the monomorphic proteasome and TAP.
PMID 18949050 · PMC2569417 · PloS one · 2008 · 6 claims · 5 setups
Within individual hosts, proteasome and TAP escape mutations in HIV-1 occur frequently
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Distinctive pattern of sequence polymorphism in the NS3 protein of hepatitis C virus type 1b reflects conflicting evolutionary pressures.
PMID 18632963 · PMC2577380 · The Journal of general virology · 2008 · 7 claims · 6 setups
NS3 shows less evidence of purifying selection acting on its CTL epitopes than the other 9 HCV proteins, while outside the CTL epitopes NS3 is more conserved than the other proteins.
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Candidate vaccine sequences to represent intra- and inter-clade HIV-1 variation.
PMID 19812689 · PMC2753653 · PloS one · 2009 · 7 claims · 5 setups
Natural CTL immunodominance toward variable proteome regions increases epitope mismatch with challenge strains and recapitulates the escape-driven CTL failure seen in natural infection, contributing to HIV vaccine failure