Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Subfunctionalization of duplicated genes as a transition state to neofunctionalization.
PMID 15831095 · PMC1112588 · BMC evolutionary biology · 2005 · 8 claims · 2 setups
Subfunctionalization plays an important role in duplicate gene retention but functions as a transition state leading to neofunctionalization rather than as a terminal fate.
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Divergence of exonic splicing elements after gene duplication and the impact on gene structures.
PMID 19883501 · PMC3091315 · Genome biology · 2009 · 8 claims · 7 setups
ESEs and ESSs diverge especially fast shortly after gene duplication, correlating with time since duplication (Ks)
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Analysis of recent segmental duplications in the bovine genome.
PMID 19951423 · PMC2796684 · BMC genomics · 2009 · 8 claims · 6 setups
Recently duplicated sequence (≥1 kb, ≥90% identity) comprises 3.11% (94.4 Mb) of the bovine genome assembly (Btau_4.0)
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Gene duplication: the genomic trade in spare parts.
PMID 15252449 · PMC449868 · PLoS biology · 2004 · 8 claims · 7 setups
Gene duplication relaxes selective constraint on one copy, allowing exploration of evolutionary space that is otherwise forbidden in single-copy genes, making duplication the major opportunity for new gene function evolution.