Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Limited protection against early-life lung murine cytomegalovirus infection results from deficiency of cytotoxic CD8 T cells.
PMID 42008567 · PMC13128127 · PLoS pathogens · 2026 · 9 claims · 9 setups
Expansion of endogenous MCMV-specific CD8 T cells is delayed in early life due to a low precursor frequency of peripheral αβ T cells
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Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine-Dependent Pro-Inflammatory Immune Microenvironment.
PMID 41580972 · PMC13042394 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 8 setups
T cell-specific Socs1 loss intrinsically drives pro-inflammatory T cell differentiation independent of antigen stimulation, with the strongest effects in CD8+ T cells
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Transient tumor exposure induces persistent functional defects in memory CD8(+) T cells.
PMID 42023146 · PMC13098610 · iScience · 2026 · 8 claims · 8 setups
Memory CD8+ T cells generated after transient tumor rejection (Tum-CD8+) display a distinct, partially exhausted phenotype compared to virus-induced memory cells (Vir-CD8+)
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TOPK Suppresses the CD8(+) T Cell Antitumor Immunity via Modulation of IRF5 Expression.
PMID 41868885 · PMC13003159 · Cancer communications (London, England) · 2026 · 8 claims · 8 setups
A TOPK+ subset of tumor-infiltrating CD8+ T cells exists in melanoma at higher frequency than in normal lymph nodes and shows suppressed cytotoxic/cytokine programs.