Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

• B-lineage commitment is dependent on a reversible epigenetic switch.

  PMID 41266087 · PMC12863259 · Genes & development · 2026 · 8 claims · 8 setups

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  B-lymphoid commitment is mediated by a transcription factor-dose-dependent epigenetic switch that suppresses inherent T-lineage potential in early lymphoid progenitors

  bone expanded pax5 ebf1 combined atac-seq chip-seq

• Novel insights into adipogenesis from omics data.

  PMID 19689276 · PMC2765082 · Current medicinal chemistry · 2009 · 8 claims · 8 setups

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  Pparg and Cebpa are the two master transcriptional regulators governing adipogenesis

  3t3-l1 embryonic multipotent nih-3t3 microarray gel non-gel-based

• An Erg-driven transcriptional program controls B cell lymphopoiesis.

  PMID 32541654 · PMC7296042 · Nature communications · 2020 · 7 claims · 8 setups

  Has reproduction · 81

  Erg is essential for early B lymphoid differentiation

  erg b220+ prob wild-type lacz rna-seq flow

• A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency.

  PMID 41649478 · PMC12880805 · eLife · 2026 · 8 claims · 8 setups

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  Mir195 transduction rescues Ebf1-deficient HPCs, inducing CD19 expression and a B-lineage gene expression program

  wild-type ebf1 nog mir195 flow cdna engraftment

• Single-cell ATAC-seq analysis of human embryoid bodies reveals crucial transcription factor networks involved in early germ layer specification.

  PMID 41906160 · PMC13154528 · Cell & bioscience · 2026 · 7 claims · 7 setups

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  scATAC-seq of human EBs can classify cells into the three germ layers and, via pseudotime analysis, identify 'early committed cells' at the onset of each germ layer.

  embryoid embryonic hescs single-cell mesendoderm neural