Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 48
Screening of Diagnostic Biomarkers and Immune Infiltration Characteristics Linking Rheumatoid Arthritis and Rosacea Based on Bioinformatics Analysis.
PMID 39104909 · PMC11299729 · Journal of inflammation research · 2024 · 8 claims · 8 setups
277 co-expressed DEGs shared between RA and rosacea are enriched in immune processes and chemokine-mediated signaling pathways
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Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study.
PMID 18205922 · PMC2374452 · Arthritis research & therapy · 2008 · 7 claims · 4 setups
A standardized 3D in vitro alginate bead model of chondrocytes stimulated with synovial fibroblast supernatants can be used to profile RA-related cartilage destruction genes
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Identification of novel citrullinated autoantigens of synovium in rheumatoid arthritis using a proteomic approach.
PMID 17125526 · PMC1794520 · Arthritis research & therapy · 2006 · 8 claims · 6 setups
51 citrullinated protein spots were detected in RA synovial tissue, of which 30 (58.8%) were autoantigenic (reactive with RA sera)
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Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma.
PMID 19956606 · PMC2779485 · PloS one · 2009 · 8 claims · 7 setups
A 100-gene signature from LSL-KrasG12D;Trp53Flox/Flox mouse sarcomas (vs normal muscle) is specifically and significantly enriched in human MFH but not other soft tissue sarcoma subtypes across three independent human datasets.
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Somatic mutations in mitochondria: the chicken or the egg?
PMID 16207343 · PMC1257449 · Arthritis research & therapy · 2005 · 6 claims · 6 setups
Patients with RA have a higher incidence of somatic mtDNA mutations (in MT-ND1 transcripts) in synoviocytes and synovial tissue compared with OA patients
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Disease-specific proteins from rheumatoid arthritis patients.
PMID 16778393 · PMC2729955 · Journal of Korean medical science · 2006 · 8 claims · 6 setups
Fibronectin, semaphorin 7A precursor, growth factor receptor-bound protein 7 (GRB7), and immunoglobulin µ chain specifically associate with antibodies purified from RA synovial fluid
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The identification and characterization of a novel protein, c19orf10, in the synovium.
PMID 17362502 · PMC1906808 · Arthritis research & therapy · 2007 · 8 claims · 8 setups
c19orf10 is a novel protein produced in significant amounts by fibroblast-like synoviocytes (FLSs), identified via proteomic analysis
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Has reproduction · 85
Protocol for transcriptomic and epigenomic analysis of JAK inhibitor sensitivity in IFN-γ-primed human macrophages using ATAC-seq and RNA-seq.
PMID 41313685 · PMC12702366 · STAR protocols · 2025 · 7 claims · 7 setups
Integrated ATAC-seq and RNA-seq protocol to profile JAK inhibitor sensitivity in IFN-γ-primed human macrophages