Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
-
Full-text index only
CD70 (TNFSF7) is expressed at high prevalence in renal cell carcinomas and is rapidly internalised on antibody binding.
PMID 16892042 · PMC2360640 · British journal of cancer · 2006 · 6 claims · 6 setups
CD70 was identified by proteomic analysis of plasma membrane preparations as highly expressed in A498 and SW839 RCC-derived cell lines
-
Full-text index only
EIF5A Couples Translational Control With Transcriptional Reprogramming Through Chromocenter Reorganization During Spermiogenesis.
PMID 41486816 · PMC12903998 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 8 setups
eIF5A is highly expressed in spermatogenic cells, particularly spermatogonia and round spermatids, across human and mouse testis
-
Has reproduction · 67
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.
PMID 28930663 · PMC5719893 · Immunity · 2017 · 8 claims · 8 setups
A common APOE-dependent microglial molecular signature (MGnD) — loss of homeostatic genes plus induction of inflammatory genes with Apoe among the most upregulated — occurs in ALS, MS and AD mouse models and around neuritic Aβ-plaques in human AD brain.
-
Full-text index only
Optimization of protein solubilization for the analysis of the CD14 human monocyte membrane proteome using LC-MS/MS.
PMID 19709643 · PMC3159575 · Journal of proteomics · 2009 · 7 claims · 5 setups
Methanol-based solubilization, alone or combined with PPS, yields significantly higher membrane protein identification/enrichment than PPS alone in monocyte membrane proteomics
-
Full-text index only
Gpc3 selectively suppresses subcutaneous adipogenesis in diet-induced obesity.
PMID 41779769 · PMC12978566 · PLoS biology · 2026 · 8 claims · 8 setups
Gpc3 is an obesity-responsive gene exhibiting reciprocal expression patterns between subcutaneous and visceral adipose depots in mice and humans
-
Has reproduction · 75
Single-cell multiomics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response.
PMID 39503729 · PMC11540304 · eLife · 2024 · 8 claims · 5 setups
CITE-seq multiomics reveals that each CML patient harbors a unique composition of stem and progenitor cells at diagnosis
-
Full-text index only
Adhesion-Related Macrophages Regulate Metabolic Homeostasis Through CAV-1 Dependency.
PMID 41817010 · PMC13159151 · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026 · 8 claims · 8 setups
Adhesion-related macrophages (ARMs) are a distinct macrophage subpopulation that adheres directly to adipocytes and can be isolated using a novel vortex/bead-based method
-
Has reproduction · 50
ZAP targets aberrant mRNA transcripts encoding proteins with defective signal peptides for degradation.
PMID 41820617 · PMC13084044 · The EMBO journal · 2026 · 8 claims · 7 setups
ZAP (ZC3HAV1/PARP13) is a key component of the RAPP quality control pathway
-
Full-text index only
Intestinal macrophages modulate synucleinopathy along the gut-brain axis.
PMID 41606336 · PMC12960212 · Nature · 2026 · 8 claims · 8 setups
ME-Macs engulf misfolded, aggregated αS and modulate αS pathology and neurodegeneration in PD mouse models