Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 11

System / cell line: co-culture ✕ Assay: flow ✕ Clear

A human tumor-immune organoid model of glioblastoma.

PMID 41505256 · PMC12969483 · Cell reports · 2026 · 8 claims · 8 setups

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iHOTT is an autologous co-culture platform integrating patient-derived tumor cells and matched PBMCs within human cortical organoids

ihott sorted recurrent flow immunostaining multiplex
Generation of thymus-reconstituting T cell progenitors from human pluripotent stem cells.

PMID 41512861 · PMC12853186 · Cell reports methods · 2026 · 7 claims · 6 setups

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A cytokine-free hPSC hematopoietic differentiation protocol followed by OP9-DLL4 stromal co-culture generates pro-T cells without genetic manipulation

hpsc hescs hpsc-hec-derived sorted flow tcr single-cell
Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3.

PMID 17459006 · PMC1890847 · Journal of thrombosis and haemostasis : JTH · 2007 · 8 claims · 8 setups

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Activated neutrophils decrease EPCR surface expression on endothelial cells over time

ea.hy926 peripheral neutrophils recombinant flow luminol-dependent sds-page
Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.

PMID 33948572 · PMC8080108 · Cell reports. Medicine · 2021 · 8 claims · 8 setups

Has reproduction · 35

Neutrophils recruited to CF airways undergo rapid, broad transcriptional firing that upregulates anabolic genes and downregulates antimicrobial genes

blood healthy transmigrated cfasn-transmigrated flow transmigration content
Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome.

PMID 39871175 · PMC11773931 · Cellular & molecular biology letters · 2025 · 8 claims · 8 setups

Has reproduction · 84

Monocytes are the primary carriers that transport Stx2 from the periphery to the kidney during STEC-induced HUS

peripheral thp-1 cfse-labeled evs single-cell flow toxin-cell
Genomic instability and mono-parental expression mitigate genomic shock in a cross-subgenus Leishmania hybrid.

PMID 41918820 · PMC13034039 · NAR molecular medicine · 2026 · 7 claims · 8 setups

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An in vitro cross between L. infantum and L. tarentolae produced a viable inter-subgenus hybrid, demonstrating genomic compatibility between highly divergent Leishmania species.

infantum linf-gfp bone bmdms genetic flow morphological
pmid-41540084

PMID 41540084 · PMC12894745 · 8 claims · 8 setups

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The presence of immune cells in the environment significantly alters CLL cell activation

autologous monoculture non-adherent pbmc bulk flow deconvolution
Tumor-specific but immunosuppressive CD39(+)CD8(+) T cells exhibit double-faceted roles in clear cell renal cell carcinoma.

PMID 40961944 · PMC12629791 · Cell reports. Medicine · 2025 · 8 claims · 8 setups

Has reproduction · 88

CD39+CD8+ TILs constitute a terminally exhausted, tumor-antigen-specific subset of CD8+ T cells

memory sorted caix-specific cd39+pd-1bright scrna-seq bulk mhc
Liver-specific paraoxonase-1 alleviates regulatory T cell-driven immunosuppression via metabolic reprogramming in hepatocellular carcinoma.

PMID 41387425 · PMC12701056 · Nature communications · 2025 · 8 claims · 8 setups

Has reproduction · 66

PON1 expression is downregulated in HCC tumor tissue and low PON1 is associated with worse prognosis

hcc paired hepa1-6 pon1-nc bioinformatic immunohistochemistry orthotopic
Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit.

PMID 41501466 · PMC12820784 · Nature · 2026 · 8 claims · 8 setups

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Inflammation-associated fibroblasts (IAFs), induced by proinflammatory FCN1+IL1B+ macrophages, produce profibrotic IL-11 and drive fibrosis in IBD

intestinal colon pdgfra+ colonic scrna-seq xenium masson's
Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct characteristics.

PMID 17331236 · PMC1868942 · Genome biology · 2007 · 8 claims · 8 setups

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moDCs and KG-1 cells show significant proteomic differences from primary mDCs, particularly in proteins involved in cell growth/maintenance and cell-cell interaction/integrity.

mdcs mdc freshly peripheral two-dimensional maldi-tof capture

Experiments

A human tumor-immune organoid model of glioblastoma.

Generation of thymus-reconstituting T cell progenitors from human pluripotent stem cells.

Proteolysis of the endothelial cell protein C receptor by neutrophil proteinase 3.

Transcriptional firing represses bactericidal activity in cystic fibrosis airway neutrophils.

Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome.

Genomic instability and mono-parental expression mitigate genomic shock in a cross-subgenus Leishmania hybrid.

pmid-41540084

Tumor-specific but immunosuppressive CD39(+)CD8(+) T cells exhibit double-faceted roles in clear cell renal cell carcinoma.

Liver-specific paraoxonase-1 alleviates regulatory T cell-driven immunosuppression via metabolic reprogramming in hepatocellular carcinoma.

Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit.

Analysis of proteomic profiles and functional properties of human peripheral blood myeloid dendritic cells, monocyte-derived dendritic cells and the dendritic cell-like KG-1 cells reveals distinct characteristics.