Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Full-text index only
CTCF/cohesin-binding sites are susceptible to replication-associated DNA damage and genomic instability in cancer cells.
PMID 41630911 · PMC12860730 · iScience · 2026 · 8 claims · 8 setups
CTCF and cohesin (RAD21) remain co-bound to DNA throughout interphase, including during the S (replication) phase, in HeLa cells
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Full-text index only
Chromatin architecture reprogramming reveals novel epigenetic dependencies in breast cancer.
PMID 41412800 · PMC12849445 · Genes & development · 2026 · 7 claims · 7 setups
H3K9 methylation and the demethylase KDM4C, through association with SWI/SNF, drive proliferation of cells fated to become endocrine-resistant via a nongenomic estrogen-mediated mechanism
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Has reproduction · 57
Genome-wide kinetic properties of transcriptional bursting in mouse embryonic stem cells.
PMID 32596448 · PMC7299619 · Science advances · 2020 · 8 claims · 8 setups
Transcriptional bursting kinetics is regulated by a combination of promoter- and gene body-binding proteins, including the polycomb repressive complex 2 (PRC2) and transcription elongation factors
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Has reproduction · 49
Aberration in DNA methylation in B-cell lymphomas has a complex origin and increases with disease severity.
PMID 23326238 · PMC3542081 · PLoS genetics · 2013 · 8 claims · 8 setups
B-cell non-Hodgkin lymphomas display striking intra-tumor (intra-sample) and inter-patient (inter-sample) cytosine methylation heterogeneity that increases progressively with disease aggressiveness (NBC<NGC<FL<GCB<ABC).