Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 88
Antibiotic Drug screening and Image Characterization Toolbox (A.D.I.C.T.): a robust imaging workflow to monitor antibiotic stress response in bacterial cells in vivo.
PMID 35707454 · PMC9178280 · F1000Research · 2021 · 8 claims · 6 setups
A.D.I.C.T. provides a robust, reproducible semi-automated imaging workflow for monitoring antibiotic stress response in bacteria in vivo
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Screening of the Fc epsilon RI-beta-gene in a Swiss population of asthmatic children: no association with E237G and identification of new sequence variations.
PMID 10427478 · PMC3851081 · Disease markers · 1998 · 8 claims · 6 setups
E237G shows no significant association with atopy or asthma in the Swiss population (3.7% in patients vs 2.6% in controls)
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The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer.
PMID 12381271 · PMC134458 · BMC genetics · 2002 · 7 claims · 8 setups
UNC93A maps within the minimal region of allele loss on 6q27 between D6S264 and D6S149, centromeric to D6S149
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Characterisation of p53 status at the gene, chromosomal and protein levels in oesophageal adenocarcinoma.
PMID 14583777 · PMC2394414 · British journal of cancer · 2003 · 8 claims · 4 setups
p53 gene mutations are infrequent in oesophageal adenocarcinoma (9.6%)
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Discovery of human inversion polymorphisms by comparative analysis of human and chimpanzee DNA sequence assemblies.
PMID 16254605 · PMC1270012 · PLoS genetics · 2005 · 8 claims · 6 setups
Comparative net alignment of human and chimpanzee genome assemblies identifies 1,576 putative inverted regions covering more than 154 Mb of DNA
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Functional analysis of human hematopoietic stem cell gene expression using zebrafish.
PMID 16089502 · PMC1166352 · PLoS biology · 2005 · 8 claims · 8 setups
277 unique transcripts are differentially expressed between Rho lo and Rho hi HSC-enriched/depleted populations, conserved across both umbilical cord blood and bone marrow
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Combinatorial Mismatch Scan (CMS) for loci associated with dementia in the Amish.
PMID 16515697 · PMC1448207 · BMC medical genetics · 2006 · 8 claims · 7 setups
CMS compares IBS allele/genotype sharing between distantly related (beyond grandparental) affected and unaffected individuals from founder populations to detect disease loci while reducing confounding from population stratification and genetic heterogeneity.
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Challenges and standards in integrating surveys of structural variation.
PMID 17597783 · PMC2698291 · Nature genetics · 2007 · 7 claims · 5 setups
There is no standard approach to collecting, assessing the quality of, or describing structural variants, risking the entire genome eventually being labeled 'structurally variant' based on uncurated nondisease-sample data.
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Human spermatozoa contain multiple targets for protein S-nitrosylation: an alternative mechanism of the modulation of sperm function by nitric oxide?
PMID 17683036 · PMC2777308 · Proteomics · 2007 · 7 claims · 5 setups
Human sperm proteins undergo S-nitrosylation upon exposure to NO donors, detectable by the biotin switch assay
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Correlations of EGFR mutations and increases in EGFR and HER2 copy number to gefitinib response in a retrospective analysis of lung cancer patients.
PMID 17626639 · PMC1952070 · BMC cancer · 2007 · 7 claims · 4 setups
EGFR mutations (exon 19 deletions, exon 21 L858R) did not correlate with gefitinib response in this cohort
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Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas.
PMID 19138956 · PMC3369271 · Cancer prevention research (Philadelphia, Pa.) · 2008 · 8 claims · 4 setups
EGFR mutations and protein overexpression are early phenomena in the pathogenesis of lung adenocarcinoma, occurring in histologically normal bronchial/bronchiolar epithelium (NBE)
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RPS4Y gene family evolution in primates.
PMID 18477388 · PMC2397393 · BMC evolutionary biology · 2008 · 8 claims · 8 setups
The duplication event giving rise to RPS4Y2 occurred after the divergence of New World monkeys, about 35 million years ago.
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Genomic activation of the EGFR and HER2-neu genes in a significant proportion of invasive epithelial ovarian cancers.
PMID 18182111 · PMC2266762 · BMC cancer · 2008 · 8 claims · 4 setups
No somatic mutations were found in the entire tyrosine kinase domain (exons 18-24) of EGFR or HER2-neu in 68 tissue samples from 52 ovarian cancer patients.
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Complex landscapes of somatic rearrangement in human breast cancer genomes.
PMID 20033038 · PMC3398135 · Nature · 2009 · 8 claims · 6 setups
There are more somatic rearrangements in some breast cancers than previously appreciated by cytogenetic methods.
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CTCF/cohesin-binding sites are susceptible to replication-associated DNA damage and genomic instability in cancer cells.
PMID 41630911 · PMC12860730 · iScience · 2026 · 8 claims · 8 setups
CTCF and cohesin (RAD21) remain co-bound to DNA throughout interphase, including during the S (replication) phase, in HeLa cells
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Parasitic connections: a patescibacterial epibiont, its methylotrophic gammaproteobacterial host, and their phages.
PMID 41805398 · PMC13059738 · mBio · 2026 · 8 claims · 7 setups
Strigamonas methylophilicida sp. nov. is a new patescibacterial genus and species within the family Absconditicoccaceae
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Single-cell sequencing reveals unexpected genetic diversity among Bodo spp. flagellates and their bacterial endosymbionts.
PMID 41848149 · PMC12999062 · Microbial genomics · 2026 · 8 claims · 8 setups
Seven single-cell genomes assembled from uncultured environmental Bodo cells represent three potentially novel Bodo species
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Out-of-frame CBX3::ALK fusion drives ALK activation and therapy response.
PMID 41887222 · PMC13130619 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
A CBX3::ALK out-of-frame fusion was identified in a patient with metastatic melanoma
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Distinct phenotypes and repertoires of bronchoalveolar and airway mucosal T cells in health and allergic asthma.
PMID 41519381 · PMC12983186 · Mucosal immunology · 2026 · 8 claims · 6 setups
BAL and endobronchial brush sampling capture phenotypically and clonally distinct T cell populations
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Single-nucleus RNA sequencing identifies a novel tenogenic heterologous differentiation in endometrial carcinosarcomas: implications for diagnosis and tumor classification.
PMID 41537454 · PMC12805614 · The Journal of pathology · 2026 · 6 claims · 7 setups
snRNA-seq identifies a novel tenogenic heterologous differentiation program (SCX, MKX, TNMD) in an endometrial carcinosarcoma