Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
-
Has reproduction · 56
Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq.
PMID 34875090 · PMC8887463 · Nucleic acids research · 2022 · 6 claims · 8 setups
Halo-seq pairs a light-activatable Halo-DBF ligand with Click chemistry to label and purify spatially defined RNA populations in living cells with high spatial specificity (~100 nm radius)
-
Full-text index only
Personalized copy number and segmental duplication maps using next-generation sequencing.
PMID 19718026 · PMC2875196 · Nature genetics · 2009 · 5 claims · 5 setups
mrFAST maps short reads to all possible locations in the reference genome, enabling read-depth-based prediction of absolute copy number in both unique and duplicated sequence, including discrimination between highly identical gene paralogs.
-
Full-text index only
CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.
PMID 41564866 · PMC12866162 · Cell reports. Medicine · 2026 · 8 claims · 8 setups
CHD1 and MAP3K7 loss additively sensitizes cancer cells to IFN-γ-induced death
-
Full-text index only
Segmental copy number amplifications are more stable than aneuploidies in the absence of selection.
PMID 41968576 · PMC13107562 · Molecular biology and evolution · 2026 · 8 claims · 6 setups
Segmental amplifications are stable in the absence of selection, whereas aneuploidies are rapidly lost and revert to single-copy genotype