Experiments

Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).

Publications 1.3k Datasets 392.5k Experiments 14

System / cell line: immune ✕ Assay: fluorescence ✕ Clear

SARS-CoV-2 infection during the first trimester leads to profound immune dysregulation at the maternal-fetal interface despite limited virus detection in placental tissues.

PMID 41974725 · PMC13249863 · Nature communications · 2026 · 8 claims · 8 setups

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SARS-CoV-2 rarely infects villous and decidual placental tissues in the first trimester despite maternal infection

villous maternal rt-qpcr fluorescence indirect
Restoring immune homeostasis in atherosclerotic plaques via inorganic violet phosphorus nano-immunotherapy.

PMID 41494534 · PMC12866099 · Cell reports. Medicine · 2026 · 8 claims · 8 setups

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VPNS@P selectively accumulates in immune cells within atherosclerotic plaques (predominantly macrophages and monocytes, partly T and B cells) with minimal off-target uptake by non-immune vascular cells

vpns@p cell-free raw264.7 bone-marrow-derived tem ros-scavenging cck-8
Profiling humoral immune responses to P. falciparum infection with protein microarrays.

PMID 18937256 · PMC3021802 · Proteomics · 2008 · 7 claims · 5 setups

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A protein microarray platform of 250 Pf proteins, individually expressed cell-free and printed unpurified, can profile serum antibody responses across donor groups of differing immune status

sera coli genomic microarray immuno-dot elisa
CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.

PMID 41564866 · PMC12866162 · Cell reports. Medicine · 2026 · 8 claims · 8 setups

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CHD1 and MAP3K7 loss additively sensitizes cancer cells to IFN-γ-induced death

a375 crc-9 ht-29 vcap whole-genome autologous incucyte
Genetics and environment distinctively shape the human immune cell epigenome.

PMID 41593234 · PMC12900638 · Nature genetics · 2026 · 8 claims · 6 setups

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Exposure-associated differentially methylated regions (eDMRs) and genotype-associated DMRs (gDMRs) show distinct genomic distributions: eDMRs are enriched at enhancers/regulatory regions, while gDMRs are predominantly found in gene bodies.

pbmcs pbmc edmrs differentially single-nucleus fluorescence-activated motif
Comprehensive immune profiling reveals IFN-γ signaling in T cells mediates parasite phagocytosis in a rodent malaria model.

PMID 41810957 · PMC13059739 · mBio · 2026 · 8 claims · 8 setups

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IFN-γ signaling in T cells contributes to the development of malaria-associated lung pathology

lungs pbnk65-infected cell-specific lung flow time-series qrt-pcr
Comprehensive cellular analysis with single-nucleus RNA-seq of archived PAXgene whole blood samples.

PMID 41844163 · PMC13030975 · Cell reports methods · 2026 · 8 claims · 7 setups

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Cell lysis (CL) nuclei isolation yields substantially more nuclei and less biased immune cell proportions than mechanical separation (MS)

frozen paxgene cl-derived thawed single-nucleus confocal brightfield
Comparative multi-omic analysis reveals conserved and derived mechanisms of fin and limb regeneration.

PMID 41571662 · PMC12923738 · Nature communications · 2026 · 8 claims · 8 setups

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Fin and limb regeneration share conserved proximal and distal blastema territory markers, DNA damage repair activation, hif1a-mediated hypoxia response, and sequential pro-/anti-inflammatory gene programs.

polypterus axolotl zebrafish regenerating single-nucleus spatial single-cell
Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.

PMID 41964110 · PMC13078244 · Gut microbes · 2026 · 8 claims · 12 setups

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Dietary CLA supplementation enhances host resistance to Salmonella Typhimurium infection

ileal mice serum culture 16s untargeted bulk
Immunopeptidome profiling in pulmonary fibrosis provides a platform for identifying therapeutic targets.

PMID 42010059 · PMC13132728 · Nature immunology · 2026 · 6 claims · 8 setups

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IPF fibrotic lung tissue shows an expanded and distinct HLA class I immunopeptidome compared to non-IPF lung tissue, enriched for peptides from fibroblast/macrophage-derived proteins involved in tissue remodeling

ipf tabula lung blm hla high-resolution scrna-seq
Development of double-positive thymocytes at single-cell resolution.

PMID 33771202 · PMC8004397 · Genome medicine · 2021 · 7 claims · 8 setups

Has reproduction · 86

DP thymocytes can be classified into blast, rearrangement, and selection subtypes, distinguishable by surface markers CD2 and Ly6d

thymocytes sorted thymocyte scrna-seq flow immunofluorescence
Intestinal macrophages modulate synucleinopathy along the gut-brain axis.

PMID 41606336 · PMC12960212 · Nature · 2026 · 8 claims · 8 setups

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ME-Macs engulf misfolded, aggregated αS and modulate αS pathology and neurodegeneration in PD mouse models

3kl sorted me-macs snca immunohistochemistry digital mass
Single-cell mitophagy signature-based artificial intelligence model enhances prediction of prognosis and immunotherapy response in non-small-cell lung cancer.

PMID 41851738 · PMC13112628 · Respiratory research · 2026 · 8 claims · 8 setups

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A six-gene MRG panel (FOS, CANX, EIF4G1, CALCOCO2, HSP90AB1, PRKAR1A) was selected via LASSO regression as prognostic markers in NSCLC.

nsclc tcga external immunotherapy single-cell bulk transcriptomic
Unveiling the NEFH+ malignant cell subtype: Insights from single-cell RNA sequencing in prostate cancer progression and tumor microenvironment interactions.

PMID 39759507 · PMC11695424 · Frontiers in immunology · 2024 · 8 claims · 8 setups

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A malignant cell subtype in PCa with high expression of NEFH was identified, located at the differentiation terminal, showing higher malignancy and association with advanced tumor lesions.

pca malignant tcga mda single-cell infercnv pseudotime

Experiments

SARS-CoV-2 infection during the first trimester leads to profound immune dysregulation at the maternal-fetal interface despite limited virus detection in placental tissues.

Restoring immune homeostasis in atherosclerotic plaques via inorganic violet phosphorus nano-immunotherapy.

Profiling humoral immune responses to P. falciparum infection with protein microarrays.

CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance.

Genetics and environment distinctively shape the human immune cell epigenome.

Comprehensive immune profiling reveals IFN-γ signaling in T cells mediates parasite phagocytosis in a rodent malaria model.

Comprehensive cellular analysis with single-nucleus RNA-seq of archived PAXgene whole blood samples.

Comparative multi-omic analysis reveals conserved and derived mechanisms of fin and limb regeneration.

Dietary conjugated linoleic acid enhances resistance to Salmonella infection by promoting PPARγ-mediated metabolic reprogramming and effector function in CD8⁺ T cells.

Immunopeptidome profiling in pulmonary fibrosis provides a platform for identifying therapeutic targets.

Development of double-positive thymocytes at single-cell resolution.

Intestinal macrophages modulate synucleinopathy along the gut-brain axis.

Single-cell mitophagy signature-based artificial intelligence model enhances prediction of prognosis and immunotherapy response in non-small-cell lung cancer.

Unveiling the NEFH+ malignant cell subtype: Insights from single-cell RNA sequencing in prostate cancer progression and tumor microenvironment interactions.