Experiments
Searchable full-text extractions: founding hypothesis, core claims, experimental setups, key results and statistics — pulled out of each paper as structure. Search a cell line, an assay or an entity (e.g. HUH7) and find every paper that worked with it. This corpus stands on its own: most entries carry no reproduction assessment (yet).
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Has reproduction · 93
7SL RNA and signal recognition particle orchestrate a global cellular response to acute thermal stress.
PMID 39952919 · PMC11828898 · Nature communications · 2025 · 8 claims · 8 setups
Heat shock induces de novo transcription and nuclear accumulation of 7SL RNA together with SRP proteins, which then bind chromatin at promoters
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Has reproduction · 45
RNA structure maps across mammalian cellular compartments.
PMID 30886404 · PMC6640855 · Nature structural & molecular biology · 2019 · 8 claims · 6 setups
icSHAPE-based cytotopic RNA structuromes across chromatin, nucleoplasm and cytoplasm in human and mouse cells substantially expand the scope of RNA structural information beyond whole-cell data.
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A novel approach to tag and identify geranylgeranylated proteins.
PMID 19784953 · PMC2855049 · Electrophoresis · 2009 · 7 claims · 7 setups
Metabolic incorporation of azido-GG alcohol followed by Cu(I)-catalyzed click reaction with TAMRA-alkyne selectively labels geranylgeranylated proteins for fluorescence detection
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Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes.
PMID 17486137 · PMC2673710 · Molecular systems biology · 2007 · 8 claims · 7 setups
Global MudPIT-based proteomic profiling across six mouse lung developmental time points (E13.5–P56) identifies thousands of proteins and captures developmental/cell-biological expression patterns.